142741-24-0 Usage
Description
Cophylline, a naturally occurring alkaloid, is derived from various plant sources and possesses unique pharmacological properties. It has been found to play a significant role in the differentiation of stem cells, particularly in the context of regenerative medicine.
Uses
Used in Regenerative Medicine:
Cophylline is used as a differentiation agent for promoting the development of adipose-derived stem cells into functional islet-like cells. This application is particularly relevant in the field of diabetes research and treatment, as these islet-like cells have the potential to be used in cell replacement therapies for patients with diabetes.
Used in Pharmaceutical Research:
In the pharmaceutical industry, Cophylline is utilized for its potential to enhance the therapeutic use of stem cells. Its role in promoting the differentiation of stem cells into specific cell types makes it a valuable compound for developing novel treatments and therapies for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 142741-24-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,7,4 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 142741-24:
(8*1)+(7*4)+(6*2)+(5*7)+(4*4)+(3*1)+(2*2)+(1*4)=110
110 % 10 = 0
So 142741-24-0 is a valid CAS Registry Number.
142741-24-0Relevant articles and documents
Biologically active indole and bisindole alkaloids from Tabernaemontana divaricata
Kam, Toh-Seok,Pang, Huey-Shen,Lim, Tuck-Meng
, p. 1292 - 1297 (2003)
The ethanol extract of the leaves of Tabernaemontana divaricata (double flower variety) provided a total of 23 alkaloids, including the new aspidosperma alkaloids, taberhanine, voafinine, N-methylvoafinine, voafinidine, voalenine and the new bisindole alkaloid, conophylinine in addition to the previously known, biologically active bisindole, conophylline and its congener, confoline. The structures of the new alkaloids were established by spectroscopic methods. The preparation and characterization of the corresponding quinones of the biologically active bisindoles are also described in relation to a structure-activity study of these compounds with respect to their action in stimulating insulin expression.
