142757-92-4

Basic information

• Product Name: <1S-(1α,2α,3α,4α)>-2-<<3-<<<1-(hydroxymethyl)-2-oxo-2-(phenylmethoxy)ethyl>amino>carbonyl>-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzenepropanoic acid methyl ester
• Synonyms: <1S-(1α,2α,3α,4α)>-2-<<3-<<<1-(hydroxymethyl)-2-oxo-2-(phenylmethoxy)ethyl>amino>carbonyl>-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzenepropanoic acid methyl ester
• CAS NO: 142757-92-4
• Molecular Weight: 495.573
• Mol File: 142757-92-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: <1S-(1α,2α,3α,4α)>-2-<<3-<<<1-(hydroxymethyl)-2-oxo-2-(phenylmethoxy)ethyl>amino>carbonyl>-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzenepropanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: <1S-(1α,2α,3α,4α)>-2-<<3-<<<1-(hydroxymethyl)-2-oxo-2-(phenylmethoxy)ethyl>amino>carbonyl>-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzenepropanoic acid methyl ester(142757-92-4)
• EPA Substance Registry System: <1S-(1α,2α,3α,4α)>-2-<<3-<<<1-(hydroxymethyl)-2-oxo-2-(phenylmethoxy)ethyl>amino>carbonyl>-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzenepropanoic acid methyl ester(142757-92-4)

Safety Data

• Hazardous Substances Data: 142757-92-4(Hazardous Substances Data)

Upstream product

• 135682-54-1 <1S-(1α,2α,3α,(S^*),4α)>-α-<2-<3-<oxy>propyl>phenyl>-7-oxabicyclo<2.2.1>heptane-2,3-dimethanol 
• 142663-80-7 <1-bromo-2-<3-<oxy>propyl>phenyl>magnesium 
• 60022-62-0 L-serine benzyl ester hydrochloride 
• 142757-91-3 <1S-(1α,2α,3α,4α)>-2-<(3-carboxy-7-oxabicyclo<2.2.1>hept-2-yl)methyl>benzenepropanoic acid methyl ester 
• 133027-60-8 Acetic acid (1R,2R,3R,4S)-3-(2-{3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-propyl}-benzyl)-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl ester 
• 135682-55-2 [(1R,2R,3R,4S)-3-(2-{3-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-propyl}-benzyl)-7-oxa-bicyclo[2.2.1]hept-2-yl]-methanol 
• 142757-90-2 [1S-(1α,2α,3α,4α)]-2-[[3-[(Acetyloxy)methyl]-7-oxabicyclo[2.2.1]hept-2-yl]methyl]benzenepropanoic acid 
• 135682-53-0 <1S-1α,2α,3α,4α>-2-<<3-(hydroxymethyl)-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzenepropanoic acid, methyl ester 
• 142758-00-7 3-[2-((1S,2R,3R,4R)-3-Hydroxymethyl-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenyl]-propionic acid 
• 404575-34-4 7-oxabicyclo<2.2.1>heptane tetrahydrofuranol 

Downstream Products

• 149079-66-3 3-(2-{(1S,2R,3S,4R)-3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-yl]-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl}-phenyl)-propionic acid benzyl ester 
• 149079-67-4 2-{(1R,2S,3R,4S)-3-[2-(2-Benzyloxycarbonyl-ethyl)-benzyl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-oxazole-4-carboxylic acid 4-cyclohexyl-butyl ester 
• 149080-18-2 3-(2-{(1S,2R,3S,4R)-3-[4-(4-Cyclohexylcarbamoyl-butylcarbamoyl)-oxazol-2-yl]-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl}-phenyl)-propionic acid methyl ester 
• 149080-16-0 3-[2-((1S,2R,3S,4R)-3-{4-[4-(4-Methylsulfanyl-phenyl)-butylcarbamoyl]-oxazol-2-yl}-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenyl]-propionic acid methyl ester 
• 149080-15-9 [1S-(1α,2α, 3α,4α)]-2-[[3-[4-[[[4-(4-Methoxyphenyl)-butyl]amino]carbonyl]-2-oxazolyl]-7-oxabicyclo-[2.2.1]hept-2-yl]methyl]benzenepropanoic acid, methyl ester 
• 149117-80-6 3-[2-((1S,2R,3S,4R)-3-{4-[4-(4-Methylsulfanyl-phenyl)-butylcarbamoyl]-oxazol-2-yl}-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenyl]-propionic acid 
• 142757-95-7 3-[2-((1S,2R,3S,4R)-3-{4-[4-(4-Chloro-phenyl)-butylcarbamoyl]-oxazol-2-yl}-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenyl]-propionic acid methyl ester 
• 149080-13-7 3-[2-((1S,2R,3S,4R)-3-{4-[4-(4-Fluoro-phenyl)-butylcarbamoyl]-oxazol-2-yl}-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenyl]-propionic acid methyl ester 
• 149080-19-3 [1S-(1α,2α,3α,4α)]-2-[[3-[4-[[(5-Carboxy-5-methylhexyl)amino]carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]-methyl]benzenepropanoic acid, methyl ester 
• 149117-78-2 [1S-(1α,2α,3α,4α)]-2-[[3-[4-[[[4-(4-hydroxyphenyl)butyl]amino]carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]methyl]benzenepropanoic acid 
• 142663-90-9 [1S-(1α,2α,3α,4α)]-2-[[3-[4-[[[2-(4-Chlorophenyl)ethyl]amino]carbonyl]-2-oxazolyl]-7-oxabicyclo[2.2.1]hept-2-yl]methyl]benzenepropanoic acid, methyl ester 
• 149117-75-9 <1S-(1α,2α,3α,4α)>-2-<<3-<4-<<(4-cyclohexylbutyl)amino>carbonyl>-2-oxazolyl>-7-oxabicyclo<2.2.1>hept-2-yl>methyl>benzenepropanoic acid ethyl ester 
• 149080-07-9 3-[2-((1S,2R,3S,4R)-3-{4-[(4-Cyclohexyl-butyl)-methyl-carbamoyl]-oxazol-2-yl}-7-oxa-bicyclo[2.2.1]hept-2-ylmethyl)-phenyl]-propionic acid methyl ester 

Relevant articles and documents

Interphenylene 7-Oxabicycloheptane Oxazoles. Highly Potent, Selective, and Long-Acting Thromboxane A2 Receptor Antagonists

A series of interphenylene 7-oxabicycloheptane oxazoles (2) were prepared and evaluated for their thromboxane (TxA2) antagonistic activity in vitro and duration of action in vivo.Examination of the carboxyl side chain indicated that the