1427691-27-7

Basic information

• Product Name: 2-methyl-5-phenylpyrazolo[1,5-c]quinazoline
• Synonyms: 2-methyl-5-phenylpyrazolo[1,5-c]quinazoline
• CAS NO: 1427691-27-7
• Molecular Weight: 259.31
• Mol File: 1427691-27-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-5-phenylpyrazolo[1,5-c]quinazoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-5-phenylpyrazolo[1,5-c]quinazoline(1427691-27-7)
• EPA Substance Registry System: 2-methyl-5-phenylpyrazolo[1,5-c]quinazoline(1427691-27-7)

Safety Data

• Hazardous Substances Data: 1427691-27-7(Hazardous Substances Data)

Upstream product

• 57279-20-6 1-(2-bromophenyl)-butane-1,3-dione 
• 727663-40-3 2-methyl-5-phenyl-5,6-dihydropyrazolo[1,5-c]quinazoline 
• 1238945-94-2 5-(2-bromophenyl)-3-methyl-1H-pyrazole 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Synthesis of pyrazolo[1,5- c ]quinazoline derivatives through copper-catalyzed tandem reaction of 5-(2-bromoaryl)-1 H -pyrazoles with carbonyl compounds and aqueous ammonia

A practical and efficient synthesis of pyrazolo[1,5-c]quinazolines and 5,6-dihydropyrazolo[1,5-c]quinazolines, including several spiro compounds, through copper-catalyzed tandem reaction of 5-(2-bromoaryl)-1H-pyrazoles with carbonyl compounds and aqueous ammonia under air has been developed. Compared with literature methods toward pyrazolo[1,5-c]quinazoline derivatives, the synthetic method reported in this paper has the advantages of readily available and inexpensive starting materials and reagents, broad scope of substrates, and mild reaction conditions.