1428098-90-1

Basic information

• Product Name: 5-(2,2-difluoro-2-(5-phenyl-1,2,4-oxadiazol-3-yl)ethyl)-3-p-tolyloxazolidin-2-one
• CAS NO: 1428098-90-1
• Molecular Weight: 385.37
• Mol File: 1428098-90-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(2,2-difluoro-2-(5-phenyl-1,2,4-oxadiazol-3-yl)ethyl)-3-p-tolyloxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2,2-difluoro-2-(5-phenyl-1,2,4-oxadiazol-3-yl)ethyl)-3-p-tolyloxazolidin-2-one(1428098-90-1)
• EPA Substance Registry System: 5-(2,2-difluoro-2-(5-phenyl-1,2,4-oxadiazol-3-yl)ethyl)-3-p-tolyloxazolidin-2-one(1428098-90-1)

Safety Data

• Hazardous Substances Data: 1428098-90-1(Hazardous Substances Data)

Upstream product

• 7625-64-1 p-tolyl-carbamic acid benzyl ester 
• 106-49-0 p-toluidine 

Relevant articles and documents

Microwave-assisted expeditious synthesis of 5-fluoroalkyl-3-(aryl/alkyl)- oxazolidin-2-ones

An efficient and convenient protocol for synthesis of 5-fluoroalkyl-3- (aryl/alkyl)-oxazolidin-2-ones is described. The reaction of allyl (aryl/alkyl) carbamates with fluoroalkyl iodide initiated by sodium dithionite in aqueous acetonitrile resulted in adducts that undergoes a cyclization assisted by microwave irradiation to form 5-fluoroalkyl-3-(aryl/alkyl)-oxazolidin-2-ones with high yields. It was also found that the products can be more efficiently formed via an AIBN-initiated one-pot addition-cyclization sequence from benzyl allyl(aryl/alkyl) carbamates and fluoroalkyl iodide.