1428157-04-3Relevant articles and documents
Directing group enhanced carbonylative ring expansions of amino-substituted cyclopropanes: Rhodium-catalyzed multicomponent synthesis of N-heterobicyclic enones
Shaw, Megan H.,Melikhova, Ekaterina Y.,Kloer, Daniel P.,Whittingham, William G.,Bower, John F.
, p. 4992 - 4995 (2013/05/22)
Aminocyclopropanes equipped with suitable N-directing groups undergo efficient and regioselective Rh-catalyzed carbonylative C-C bond activation. Trapping of the resultant metallacycles with tethered alkynes provides an atom-economic entry to diverse N-heterobicyclic enones. These studies provide a blueprint for myriad N-heterocyclic methodologies.