1428236-59-2Relevant articles and documents
Highly enantioselective Friedel-Crafts alkylation/N-hemiacetalization cascade reaction with indoles
Cheng, Hong-Gang,Lu, Liang-Qiu,Wang, Tao,Yang, Qing-Qing,Liu, Xiao-Peng,Li, Yang,Deng, Qiao-Hui,Chen, Jia-Rong,Xiao, Wen-Jing
supporting information, p. 3250 - 3254 (2013/04/10)
A new ring for your indole: An unprecedented copper-catalyzed enantioselective Friedel-Crafts alkylation/N-hemiacetalization cascade reaction with indoles and β,γ-unsaturated α-ketoesters is reported. This mild strategy provides new access to various synthetically and biologically important 2,3-dihydro-1H-pyrrolo[1,2-a]indoles in a highly enantioselective manner.