142834-59-1Relevant articles and documents
Second-generation auxiliary for the asymmetric addition of metalated tetrahydroisoquinolines to aldehydes
Zhang, Pingsheng,Gawley, Robert E.
, p. 2945 - 2948 (1992)
The selectivity of asymmetric addition of tetrahydroisoquinolyloxazoline Grignard reagents to aldehydes has now been improved to 78-82% ds through the use of a camphor-derived auxiliary. The new auxiliary has broad applicability, with overall yields of ch