1428536-63-3

Basic information

• Product Name: 8,9-dimethyl-3-(p-toluenesulfonyl)-1-vinyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
• Synonyms: 8,9-dimethyl-3-(p-toluenesulfonyl)-1-vinyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine
• CAS NO: 1428536-63-3
• Molecular Weight: 355.501
• Mol File: 1428536-63-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8,9-dimethyl-3-(p-toluenesulfonyl)-1-vinyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine(CAS DataBase Reference)
• NIST Chemistry Reference: 8,9-dimethyl-3-(p-toluenesulfonyl)-1-vinyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine(1428536-63-3)
• EPA Substance Registry System: 8,9-dimethyl-3-(p-toluenesulfonyl)-1-vinyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine(1428536-63-3)

Safety Data

• Hazardous Substances Data: 1428536-63-3(Hazardous Substances Data)

Upstream product

• 17283-14-6 3,4-dimethylphenethylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 1428536-70-2 N-(3,4-dimethylphenethyl)toluenesulfonamide 

Relevant articles and documents

Synthesis of 3-benzazepines and azepino[4,5-b]heterocyclic ring systems via intramolecular Friedel-Crafts cyclization

The intramolecular Friedel-Crafts cyclization was found to be effective for the synthesis of 3-benzazepines and azepino[4,5-b]heterocyclic ring systems using simple allylic bromides tethered to activated aromatic nuclei. Amongst the various Lewis acids screened, Bi(OTf)3 was found to be the most effective 'ecofriendly' catalyst for the cyclization.