1428538-05-9Relevant articles and documents
Backbone-Modified C2-Symmetrical Chiral Bisphosphine TMS-QuinoxP*: Asymmetric Borylation of Racemic Allyl Electrophiles
Imamoto, Tsuneo,Ito, Hajime,Iwamoto, Hiroaki,Ozawa, Yu,Takenouchi, Yuta
, p. 6413 - 6422 (2021/05/31)
A new C2-symmetrical P-chirogenic bisphosphine ligand with silyl substituents on the ligand backbone, (R,R)-5,8-TMS-QuinoxP*, has been developed. This ligand showed higher reactivity and enantioselectivity for the direct enantioconvergent borylation of cy
Enantiospecific, regioselective cross-coupling reactions of secondary allylic boronic esters
Chausset-Boissarie, Laetitia,Ghozati, Kazem,Labine, Emily,Chen, Jack L.-Y.,Aggarwal, Varinder K.,Crudden, Cathleen M.
supporting information, p. 17698 - 17701 (2014/01/17)
An original syn: The first enantioselective Suzuki-Miyaura cross-coupling of chiral, enantioenriched secondary allylic boronic esters is described (see scheme; DME=dimethoxyethane, Bpin = pinacolboryl, dba = dibenzylideneacetone). Mechanistic studies show that the reactions proceed via γ-selective transmetalation followed by reductive elimination. The reaction provides the first independent confirmation that the transmetalation of boronic esters proceeds via a syn pathway. Copyright
