1428628-97-0Relevant articles and documents
Transmembrane halogen-bonding cascades
Vargas Jentzsch, Andreas,Matile, Stefan
supporting information, p. 5302 - 5303 (2013/05/23)
Halogen bonds have recently been introduced as ideal to transport anions across lipid bilayer membranes. However, activities obtained with small transporters were not impressive, and cyclic arrays of strong halogen-bond donors above a calix[4]arene scaffold gave even weaker activities. Here, we report that their linear alignment for anion hopping along transmembrane rigid-rod scaffolds gives excellent activities with an unprecedented cooperativity coefficient m = 3.37.