142867-52-5 Usage
General Description
N-Acetyl-N-Acetoxy-4-Chlorobenzenesulfonamide is a chemical compound known for its use in various industrial applications. It belongs to the class of organic compounds known as benzenesulfonamides. These are organosulfur compounds containing a benzenesulfonamide moiety, which consists of a benzenesulfonic acid moiety linked to an aniline or substituted aniline. The chemical formula of N-Acetyl-N-Acetoxy-4-Chlorobenzenesulfonamide is C10H10ClNO5S. Its detailed properties and toxicological profile have been studied, and safety precautions should be taken when handling this material.
Check Digit Verification of cas no
The CAS Registry Mumber 142867-52-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,8,6 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 142867-52:
(8*1)+(7*4)+(6*2)+(5*8)+(4*6)+(3*7)+(2*5)+(1*2)=145
145 % 10 = 5
So 142867-52-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H10ClNO5S/c1-7(13)12(17-8(2)14)18(15,16)10-5-3-9(11)4-6-10/h3-6H,1-2H3
142867-52-5Relevant articles and documents
Optimization of HNO production from N, O - Bis -acylated hydroxylamine derivatives
Sutton, Art D.,Williamson, Morgan,Weismiller, Hilary,Toscano, John P.
supporting information; experimental part, p. 472 - 475 (2012/03/26)
A wide range of N,O-bis-acylated hydroxylamine derivatives with chloro or arenesulfonyl leaving groups, and a related set of N-hydroxy-N-acylsulfonamides, have been synthesized and evaluated for nitroxyl (HNO) production. Mechanistic studies have revealed that the observed aqueous chemistry is more complicated than originally anticipated, and have been used to develop a new series of efficient HNO precursors (4u-4x, 7c-7d) with tunable half-lives.
Prodrugs of Nitroxyl as Inhibitors of Aldehyde Dehydrogenase
Lee, Melinda J. C.,Nagasawa, Herbert T.,Elberling, James A.,DeMaster, Eugene G.
, p. 3648 - 3652 (2007/10/02)
In the preceding paper, analogs of chlorpropamide with an OMe substituent on the sulfonamide nitrogen were shown to inhibit aldehyde dehydrogenase (AlDH), and it was postulated that these compounds were bioactivated by O-demethylation to release nitroxyl
