1428955-84-3Relevant articles and documents
Three-component condensation for the construction of novel spirooxindoles
Ji, Fei,Sun, Mu,Lv, Mei-Fang,Yi, Wen-Bin,Cai, Chun
, p. 375 - 381 (2013)
A new route for the synthesis of novel spirooxindoles from isocyanides, dialkyl acetylenedicarboxylates, and N-substituted isatylidene derivatives through [3+2] cycloaddition has been developed. This method has several advantages, such as high regioselectivity, high yields, readily available starting materials, and one-pot operations. The synthetic alkyne-containing spirooxindoles could also be used in the selective synthesis of triazole-containing-spirocyclic compounds using a copper azide-alkyne cycloaddition-(CuAAC) reaction. Georg Thieme Verlag Stuttgart · New York.