1429043-78-6

Basic information

• Product Name: N-benzyl-N-cyclopent-1-enyl-isonicotinamide
• Synonyms: N-benzyl-N-cyclopent-1-enyl-isonicotinamide
• CAS NO: 1429043-78-6
• Molecular Weight: 278.354
• Mol File: 1429043-78-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-cyclopent-1-enyl-isonicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-cyclopent-1-enyl-isonicotinamide(1429043-78-6)
• EPA Substance Registry System: N-benzyl-N-cyclopent-1-enyl-isonicotinamide(1429043-78-6)

Safety Data

• Hazardous Substances Data: 1429043-78-6(Hazardous Substances Data)

Upstream product

• 120-92-3 cyclopentanone 
• 100-46-9 benzylamine 
• 14254-57-0 4-(chlorocarbonyl)pyridine 
• 15814-19-4 N-cyclopentylidene-1-phenylmethanamine 
• 55-22-1 pyridine-4-carboxylic acid 

Downstream Products

• 1429044-22-3 1-benzyl-1'-(2,2,2-trifluoroacetyl)-4,5-dihydro-1H,1'H-spiro[cyclopenta[b]pyrrole-3,4'-pyridin]-2(3aH)-one 
• 1429043-90-2 1-benzyl-1’-(trifluoromethylsulfonyl)-4,5-dihydro-1H,1’Hspiro[cyclopenta[b]pyrrole-3,4’-pyridin]-2(3aH)-one 
• 1429044-06-3 C₂₀H₂₀N₂O₃ 
• 1429044-05-2 methyl-1-benzyl-2-oxo-2,3a,4,5-tetrahydro-1H,1'H-spiro[cyclopenta[b]pyrrole-3,4'-pyridine]-1’carboxylate 
• 1429044-15-4 2,2,2-trichloroethyl-1-benzyl-2-oxo-2,3a,4,5-tetrahydro-1H,1'H-spiro[cyclopenta[b]pyrrole-3,4'-pyridine]-1’carboxylate 

Relevant articles and documents

Spirocyclic dihydropyridines by electrophile-induced dearomatizing cyclization of N-alkenyl pyridinecarboxamides

On treatment with acylating or sulfonylating agents, N-alkenyl pyridine carboxamides (N-pyridinecarbonyl enamines) undergo a dearomatizing cyclization initiated by pyridine acylation and followed by intramolecular trapping of the resulting pyridinium cation. The products are spirocyclic dihydropyridines which may be further elaborated to spirocyclic heterocycles with drug-like features.