142929-49-5 Usage
Description
Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy](9CI) is a chemical compound characterized by a t-Boc protected amine on one end and a carboxyl group on the other end. Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy](9CI) features a single PEG (polyethylene glycol) unit, which enhances its solubility in aqueous media. The terminal carboxylic acid is capable of reacting with primary amine groups in the presence of activators, such as EDC or HATU, to form a stable amide bond. The Boc group can be removed under mild acidic conditions, revealing the free amine. It is a white crystalline powder in its chemical form.
Uses
1. Used as a Crosslinker:
Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy](9CI) is utilized as a crosslinker in various applications due to its ability to form stable amide bonds with primary amine groups when activated.
2. Used in Pharmaceutical and Biochemical Research:
In the pharmaceutical and biochemical research industries, this compound serves as a valuable tool for the synthesis of complex molecules and the study of protein-protein interactions, among other applications.
3. Used in Drug Delivery Systems:
The hydrophilic PEG spacer in Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy](9CI) can be advantageous in drug delivery systems, potentially improving the solubility and bioavailability of therapeutic agents.
4. Used in Chemical Synthesis:
Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy](9CI) can be employed in the synthesis of various organic molecules, taking advantage of its reactive carboxylic acid and Boc-protected amine groups.
5. Used in Material Science:
The unique properties of Acetic acid, [2-[[(1,1-dimethylethoxy)carbonyl]amino]ethoxy](9CI) may find applications in the development of new materials with specific characteristics, such as improved solubility or reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 142929-49-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,9,2 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 142929-49:
(8*1)+(7*4)+(6*2)+(5*9)+(4*2)+(3*9)+(2*4)+(1*9)=145
145 % 10 = 5
So 142929-49-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H17NO5/c1-9(2,3)15-8(13)10-4-5-14-6-7(11)12/h4-6H2,1-3H3,(H,10,13)(H,11,12)
142929-49-5Relevant articles and documents
INHIBITORS OF SOLUBLE ADENYLYL CYCLASE
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, (2020/06/08)
Provided are 6-amino substituted 2,6-diamino-4-choropyrimidine compounds which are specific inhibitors of soluble adenylyl cyclase. The compounds can be formulated with pharmaceutical carriers and used for reducing cyclic AMP levels. The compositions can
CONJUGATES COMPRISING HYDROXYALKYL STARCH AND A CYTOTOXIC AGENT AND PROCESS FOR THEIR PREPARATION
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Paragraph 1159-1161, (2015/11/18)
The present invention relates to a hydroxyalkyl starch conjugate and a method for preparing the same, said hydroxyalkyl starch conjugate comprising a hydroxyalkyl starch derivative and a cytotoxic agent, the cytotoxic agent comprising at least one secondary hydroxyl group, wherein the hydroxyalkyl starch is linked via said secondary hydroxyl group to the cytotoxic agent. The conjugate according to the present invention has a structure according to the following formula HAS′(-L-M)n wherein M is a residue of the cytotoxic agent, L is a linking moiety, HAS′ is the residue of the hydroxyalkyl starch derivative, and n is greater than or equal to 1, and wherein the hydroxyalkyl starch derivative has a mean molecular weight (MW) above the renal threshold.
Concise synthesis of N-protected carboxyalkyl ether amines
Adamczyk, Maciej,Fishpaugh, Jeffrey R.,Thiruvazhi, Mohan
, p. 326 - 331 (2007/10/03)
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