14293-24-4

Basic information

• Product Name: 2,5-DIMETHOXYPHENYLACETONE
• Synonyms: 1-(2,5-Dimethoxyphenyl)acetone;2,5-DIMETHOXYPHENYLACETONE;1-(2,5-Dimethoxyphenyl)-2-propanone;Methyl 2,5-dimethoxybenzyl ketone;1-(2,5-dimethoxyphenyl)propan-2-one
• CAS NO: 14293-24-4
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Product Categories: Aromatic Ketones (substituted)
• Mol File: 14293-24-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 290.1°C at 760 mmHg
• Flash Point: 120.1°C
• Appearance: /
• Density: 1.056g/cm³
• Vapor Pressure: 0.00211mmHg at 25°C
• Refractive Index: 1.497
• CAS DataBase Reference: 2,5-DIMETHOXYPHENYLACETONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHOXYPHENYLACETONE(14293-24-4)
• EPA Substance Registry System: 2,5-DIMETHOXYPHENYLACETONE(14293-24-4)

Safety Data

• Hazardous Substances Data: 14293-24-4(Hazardous Substances Data)

Usage

Description

2,5-DIMETHOXYPHENYLACETONE, also known as 2,5-dimethoxybenzylacetone, is a chemical compound with the molecular formula C11H14O3. It is a pale yellow liquid with a sweet, floral odor and is known for its stability and relatively low toxicity. This versatile compound has a variety of applications in the chemical and fragrance industries.

Uses

Used in Fragrance Industry:
2,5-DIMETHOXYPHENYLACETONE is used as a synthetic musk and floral note for its sweet, floral odor, adding depth and complexity to fragrances.
Used in Pharmaceutical Industry:
2,5-DIMETHOXYPHENYLACETONE is used as a precursor in the synthesis of various pharmaceuticals and organic compounds, contributing to the development of new medications and chemical products.

InChI:InChI=1/C11H14O3/c1-8(12)6-9-7-10(13-2)4-5-11(9)14-3/h4-5,7H,6H2,1-3H3

Upstream product

• 1758-25-4 (2,5-dimethoxyphenyl)acetic acid 
• 18790-57-3 (E)-1,4-dimethoxy-2-(2-nitroprop-1-en-1-yl) benzene 
• 25245-34-5 1-bromo-2,5-dimethoxybenzene 
• 78-95-5 chloroacetone 
• 67-64-1 acetone 
• 150-78-7 1,4-dimethoxybezene 
• 40180-96-9 2-(β-hydroxypropyl)-1,4-dimethoxybenzene 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 134040-27-0 2,5-dimethoxy-β-methyl-β-nitrostyrene 

Downstream Products

• 43021-98-3 3-(2,5-dimethoxyphenyl)-2-oximinopropane 
• 67707-78-2 N,N-dimethyl-2-(2,5-dimethoxyphenyl)isopropylamine 
• 86432-48-6 4-(2,5-Dimethoxy-phenyl)-3-hydroxy-3-methyl-butyric acid ethyl ester 
• 152093-84-0 3-(2,5-dimethoxyphenyl)-2-propylidenemalononitrile 
• 170753-14-7 3-(2',5'-dimethoxyphenyl)butan-2-one 
• 6769-56-8 2-methyl-5-hydroxy-benzofuran 
• 170753-16-9 6-(2',5'-dimethoxyphenyl)-3-methoxy-6-methylcyclohex-2-enone 
• 170753-15-8 4-(2,5-Dimethoxy-phenyl)-4-methyl-cyclohexane-1,3-dione 
• 195001-15-1 4-(2,5-Dimethoxy-phenyl)-4-methyl-3-(1-trimethylsilanyl-vinyl)-cyclohex-2-enone 
• 152093-90-8 2-amino-3-cyano-5-(2',5'-dimethoxyphenyl)-4-methylthiophene 
• 1188412-59-0 (R)-1-(2,5-dimethoxyphenyl)propan-2-ol 
• 609771-69-9 (2S)-1-(2,5-dimethoxyphenyl)-2-propanol 

Relevant articles and documents

Pigments of Fungi. LIX - Synthesis of (1S,3S)- and (1R,3R)-austrocortilutein and (1S,3S)-austrocortirubin from citramalic acid

The naturally occurring tetrahydroanthraquinone (1S,3S)-austrocortilutein (1) is synthesized for the first time in enantiomerically pure form by Diels-Alder cycloaddition between the functionalized butadiene derivative (8) and the chiral 1,3-dihydroxy-1,2,3,4-tetrahydro-5,8-naphthoquinone (9), the latter being derived from (R)-citramalic acid (3). The natural products (1S,3S)-austrocortirubin (2) and (1R,3R)-austrocortilutein (5) were also prepared for the first time by using the same strategy. CSIRO 2000.

Nickel-catalyzed direct electrochemical cross-coupling between aryl halides and activated alkyl halides

The electrochemical reduction of a mixture of aryl halides and activated alkyl halides in DMF in the presence of catalytic amount of NiBr2bipy leads to cross-coupling products in good to high yields. The method applies to the synthesis of α-aryl ketones, α-aryl esters, and allylated compounds from readily available organic halides. Optimization of the process has been obtained by slowly adding the most reactive organic halide (usually the activated alkyl halide) during the electrolysis which is best conducted at 70 °C when aryl bromides are involved.