1429347-29-4

Basic information

• Product Name: (4-butyl-2-methylphenyl)(2-methylpropyl)amine
• Synonyms: (4-butyl-2-methylphenyl)(2-methylpropyl)amine
• CAS NO: 1429347-29-4
• Molecular Weight: 219.37
• Mol File: 1429347-29-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4-butyl-2-methylphenyl)(2-methylpropyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: (4-butyl-2-methylphenyl)(2-methylpropyl)amine(1429347-29-4)
• EPA Substance Registry System: (4-butyl-2-methylphenyl)(2-methylpropyl)amine(1429347-29-4)

Safety Data

• Hazardous Substances Data: 1429347-29-4(Hazardous Substances Data)

Upstream product

• 72072-16-3 4-butyl-2-methyl-aniline 
• 78-83-1 2-methyl-propan-1-ol 

Downstream Products

• 1429347-00-1 3-[(4-{[(4-butyl-2-methylphenyl)(2-methylpropyl)amino]sulfonyl}-2-methylphenyl)oxy]propanoic acid 
• 1429347-19-2 2-(4-(N-(4-butyl-2-methylphenyl)-N-isobutylsulfamoyl)-2-methylphenoxy)acetic acid 

Relevant articles and documents

INDAZOLE SULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T))

Indazole sulfonamide derivatives of formula (I), the pharmaceutically acceptable addition salts thereof, the hydrates and/or solvates thereof, and the use of same as inverse agonists of retinoid-related orphan receptor gamma RORγt are described. Pharmaceutical compositions including such compounds, as well as the use thereof for the topical and/or oral treatment of RORγt receptor-mediated inflammatory diseases, in particular acne, psoriasis and/or atopic dermatitis are also described.

SULFONAMIDE COMPOUNDS AND THEIR USE IN THE MODULATION RETINOID - RELATED ORPHAN RECEPTOR

The present invention is directed to novel retinoid-related orphan receptor gamma (RORy) modulators of formula (I), processes for their preparation, pharmaceutical compositions containing these modulators, and their use in the treatment of inflammatory, metabolic and autoimmune diseases mediated by RORy wherein R1 to R7 are as defined in claim 1.