1429382-74-0

Basic information

• Product Name: tert-butyl (1R,2S)-2-(3-chloro-5-fluorophenyl)-1-(4-chlorophenyl)-2-hydroxyethylcarbamate
• Synonyms: tert-butyl (1R,2S)-2-(3-chloro-5-fluorophenyl)-1-(4-chlorophenyl)-2-hydroxyethylcarbamate
• CAS NO: 1429382-74-0
• Molecular Weight: 400.277
• Mol File: 1429382-74-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (1R,2S)-2-(3-chloro-5-fluorophenyl)-1-(4-chlorophenyl)-2-hydroxyethylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (1R,2S)-2-(3-chloro-5-fluorophenyl)-1-(4-chlorophenyl)-2-hydroxyethylcarbamate(1429382-74-0)
• EPA Substance Registry System: tert-butyl (1R,2S)-2-(3-chloro-5-fluorophenyl)-1-(4-chlorophenyl)-2-hydroxyethylcarbamate(1429382-74-0)

Safety Data

• Hazardous Substances Data: 1429382-74-0(Hazardous Substances Data)

Upstream product

• 1429382-72-8 (R)-tert-butyl 1-(4-chlorophenyl)-2-oxoethylcarbamate 
• 33863-76-2 1-bromo-3-chloro-5-fluorobenzene 
• 1429382-71-7 (R)-tert-butyl (1-(4-chlorophenyl)-2-hydroxyethyl)carbamate 
• 43189-37-3 (R)-2-amino-2-(4-chlorophenyl)acetic acid 
• 1067658-27-8 (R)-2-amino-2-(4-chlorophenyl)ethanol 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER

The present invention provides MDM2 inhibitor compounds of Formula I or II, or the pharmaceutically acceptable salts thereof, wherein the variables are defined above, which compounds are useful as therapeutic agents, particularly for the treatment of cancers. The present invention also relates to pharmaceutical compositions that contain an MDM2 inhibitor.