1429391-70-7Relevant articles and documents
CaF2 catalyzed SN2 type chlorodehydroxylation of chiral secondary alcohols with thionyl chloride: A practical and convenient approach for the preparation of optically active chloroalkanes
Zhang, Junjie,Wang, Huanxia,Ma, Yun,Wang, Youming,Zhou, Zhenghong,Tang, Chuchi
, p. 2261 - 2263 (2013)
A CaF2 catalyzed chlorodehydroxylation of chiral secondary alcohols with thionyl chloride has been developed. The chlorination reaction is effective for a wide range of alcohols, generating the corresponding chloroalkanes in good yield with high optical purity with inversion of the original configuration of the alcohol.