14294-33-8

Basic information

• Product Name: 3-Methylbiphenyl-2-amine
• Synonyms: 3-Methylbiphenyl-2-amine;[1,1'-Biphenyl]-2-amine, 3-methyl-;2-methyl-6-phenylaniline
• CAS NO: 14294-33-8
• Molecular Formula: C₁₃H₁₃N
• Molecular Weight: 183.25
• Mol File: 14294-33-8.mol
• Article Data: 16

Chemical Properties

• Melting Point: 61-62 °C
• Boiling Point: 309.3±11.0 °C(Predicted)
• Appearance: /
• Density: 1.057±0.06 g/cm3(Predicted)
• PKA: 3.67±0.10(Predicted)
• CAS DataBase Reference: 3-Methylbiphenyl-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methylbiphenyl-2-amine(14294-33-8)
• EPA Substance Registry System: 3-Methylbiphenyl-2-amine(14294-33-8)

Safety Data

• Hazardous Substances Data: 14294-33-8(Hazardous Substances Data)

Usage

General Description

3-Methylbiphenyl-2-amine (commonly known as 3-MBA) is an aromatic amine compound that consists of a biphenyl ring with a methyl group at the 3-position and an amine group at the 2-position. It is used as a building block in the synthesis of various pharmaceuticals and organic compounds. 3-MBA has been studied for its potential therapeutic applications, including as an anti-inflammatory and anti-cancer agent. Additionally, it is utilized in the production of polymers, dyes, and other industrial chemicals. However, it is important to handle and use 3-MBA with caution, as it is classified as a hazardous material due to its potential toxic and environmental effects.

Upstream product

• 82617-45-6 3-methyl-2-nitro-[1,1 '-biphenyl] 
• 87-63-8 2-chloro-6-methylaniline 
• 98-80-6 phenylboronic acid 
• 53848-17-2 2-bromo-6-methylaniline 
• 601-87-6 3-methyl-2-nitroaniline 
• 71-43-2 benzene 
• 14294-35-0 N-(3-methyl-[1,1'-biphenyl]-2-yl)formamide 
• 94-69-9 2'-methylformanilide 
• 95-53-4 o-toluidine 
• 52414-97-8 1-bromo-3-methyl-2-nitro-benzene 

Downstream Products

• 112422-10-3 4-Fluoro-N-(3-methyl-biphenyl-2-yl)-benzamide 
• 112422-08-9 3-Chloro-N-(3-methyl-biphenyl-2-yl)-benzamide 
• 112422-06-7 2-Chloro-N-(3-methyl-biphenyl-2-yl)-benzamide 
• 112421-98-4 N-(2-methyl-6-phenylphenyl)benzamide 
• 112422-11-4 4-Chloro-N-(3-methyl-biphenyl-2-yl)-benzamide 
• 112422-15-8 4-Methoxy-N-(3-methyl-biphenyl-2-yl)-benzamide 
• 112422-12-5 4-Bromo-N-(3-methyl-biphenyl-2-yl)-benzamide 
• 112422-13-6 4-Iodo-N-(3-methyl-biphenyl-2-yl)-benzamide 
• 112421-99-5 4-methyl-6-phenylphenanthridine 
• 112422-17-0 6-(2-Chloro-phenyl)-4-methyl-phenanthridine 
• 112422-21-6 6-(4-Fluoro-phenyl)-4-methyl-phenanthridine 
• 112422-19-2 6-(3-Chloro-phenyl)-4-methyl-phenanthridine 
• 112422-22-7 6-(4-Chloro-phenyl)-4-methyl-phenanthridine 
• 112422-23-8 6-(4-Bromo-phenyl)-4-methyl-phenanthridine 

Relevant articles and documents

A ratiometric probe for the selective time-gated luminescence detection of potassium in water

A europium probe for the ratiometric detection of potassium in water is presented. This probe demonstrates high sensitivity, with an affinity for K + in the mM range, and high selectivity for K+ over Na+, Ca2+, Mg2+ and Li+. The long luminescence lifetime of the probe and its large Stokes shift further enable accurate determination of the concentration of K+ in complex aqueous media.

Additive-free radical cascade reaction of oxime esters: Synthesis of pyrroline-functionalized phenanthridines

A variety of dihydropyrrole-functionalized phenanthridines were efficiently synthesized by the metal-free, radical cascade cyclization reaction of 2-isocyanobiphenyls with γ,δ- unsaturated oxime esters. The C-N/C-C/C-C bonds were formed via the oil bath method in a one-pot procedure with broad substrate applicability. The radical process was supported by kinetic isotope effect studies and radical inhibition studies.

Electrochemical initiation of electron-catalyzed phenanthridine synthesis by trifluoromethylation of isonitriles

The electron-catalyzed formation of phenanthridines starting from isonitriles initiated by an electrochemical reduction of the Togni reagent is presented. The required number of faradays per mole of starting material and the respective yields clearly show the catalytic character of the electron in this reaction. The mechanism is supported by cyclic voltammetry experiments.