1429442-65-8

Basic information

• Product Name: (1-(4-methoxyphenyl)cyclohexyl)(phenyl)methanone
• Synonyms: (1-(4-methoxyphenyl)cyclohexyl)(phenyl)methanone
• CAS NO: 1429442-65-8
• Molecular Weight: 294.393
• Mol File: 1429442-65-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1-(4-methoxyphenyl)cyclohexyl)(phenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1-(4-methoxyphenyl)cyclohexyl)(phenyl)methanone(1429442-65-8)
• EPA Substance Registry System: (1-(4-methoxyphenyl)cyclohexyl)(phenyl)methanone(1429442-65-8)

Safety Data

• Hazardous Substances Data: 1429442-65-8(Hazardous Substances Data)

Upstream product

• 36263-51-1 1-(4-methoxyphenyl)cyclohexane carbonitrile 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 1429442-39-6 (S)-N-((1-(4-methoxyphenyl)cyclohexyl)(phenyl)methylene)-2-methylpropane-2-sulfinamide 
• 1429442-40-9 (S)-2-((S)-1,1-dimethylethylsulfinamido)-N,N-diethyl-2-(1-(4-methoxyphenyl)cyclohexyl)-2-phenylacetamide 

Relevant articles and documents

Carbamoyl anion addition to N -sulfinyl imines: Highly diastereoselective synthesis of α-amino amides

Carbamoyl anions, generated from N,N-disubstituted formamides and lithium diisopropylamide, add with high diastereoselectivity to chiral N-sulfinyl aldimines and ketimines to provide α-amino amides. The methodology enables the direct introduction of a carbonyl group without the requirement of unmasking steps as with other nucleophiles. The products may be converted to α-amino esters or 1,2-diamines. Iterative application of the reaction enabled the stereoselective synthesis of a dipeptide. Spectroscopic and computational studies support an anion structure with η2 coordination of lithium by the carbonyl group.