142997-59-9

Basic information

• Product Name: 1-Hydroxyethyl-2'-deoxyadenosine
• Synonyms: 1-Hydroxyethyl-2'-deoxyadenosine;2'-Deoxy-1-(2-hydroxyethyl)adenosine
• CAS NO: 142997-59-9
• Molecular Formula: C12H17N5O4
• Molecular Weight: 295.29448
• Product Categories: Bases & Related Reagents;Carbohydrates & Derivatives;Nucleotides;Carbohydrates & Derivatives, Nucleotides, Bases & Related Reagents
• Mol File: 142997-59-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO, Methanol
• CAS DataBase Reference: 1-Hydroxyethyl-2'-deoxyadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Hydroxyethyl-2'-deoxyadenosine(142997-59-9)
• EPA Substance Registry System: 1-Hydroxyethyl-2'-deoxyadenosine(142997-59-9)

Safety Data

• Hazardous Substances Data: 142997-59-9(Hazardous Substances Data)

Usage

Description

1-Hydroxyethyl-2'-deoxyadenosine, also known as 1-HE2dAdo, is a synthetic nucleoside analog with significant biological and chemical properties. It is a pale yellow low melting solid that has been found to form a DNA adduct in relation to the in vitro reaction of ethylene oxide with DNA. This unique characteristic makes it a promising candidate for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
1-Hydroxyethyl-2'-deoxyadenosine is used as a pharmaceutical compound for its potential role in the development of new drugs. Its ability to form a DNA adduct with ethylene oxide makes it a valuable tool in the study of DNA interactions and the development of targeted therapies for various diseases.
Used in Research and Development:
1-Hydroxyethyl-2'-deoxyadenosine is used as a research tool for studying the mechanisms of DNA adduct formation and the effects of ethylene oxide on DNA structure and function. This knowledge can be applied to develop better understanding of DNA damage and repair processes, as well as to design more effective drugs and therapies.
Used in Chemical Synthesis:
1-Hydroxyethyl-2'-deoxyadenosine is used as a chemical intermediate in the synthesis of other nucleoside analogs and related compounds. Its unique structure and properties make it a valuable building block for the development of new molecules with potential applications in various fields, including pharmaceuticals, materials science, and biotechnology.
Used in Environmental Monitoring:
1-Hydroxyethyl-2'-deoxyadenosine can be used as a biomarker for the detection and monitoring of ethylene oxide exposure in various environmental and occupational settings. Its formation as a DNA adduct can provide valuable information about the potential health risks associated with exposure to this hazardous compound.