1430100-73-4

Basic information

• Product Name: 1-(3'-phenylquinoxalin-2'-yl)-3-(4-methoxyphenyl)-5-methylpyrazole
• Synonyms: 1-(3'-phenylquinoxalin-2'-yl)-3-(4-methoxyphenyl)-5-methylpyrazole
• CAS NO: 1430100-73-4
• Molecular Weight: 392.46
• Mol File: 1430100-73-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3'-phenylquinoxalin-2'-yl)-3-(4-methoxyphenyl)-5-methylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3'-phenylquinoxalin-2'-yl)-3-(4-methoxyphenyl)-5-methylpyrazole(1430100-73-4)
• EPA Substance Registry System: 1-(3'-phenylquinoxalin-2'-yl)-3-(4-methoxyphenyl)-5-methylpyrazole(1430100-73-4)

Safety Data

• Hazardous Substances Data: 1430100-73-4(Hazardous Substances Data)

Upstream product

• 1504-78-5 2-hydroxy-3-phenylquinoxaline 
• 23263-96-9 3-(4-methoxyphenyl)-5-methyl-1H-pyrazole 
• 7065-92-1 2-chloro-3-phenylquinoxaline 
• 4023-80-7 1-(4-methoxyphenyl)butan-1,3-dione 
• 1025-22-5 2-hydrazino-3-phenylquinoxaline 

Relevant articles and documents

Facile and efficient regioselective synthesis of 1-(3′-substituted quinoxalin-2′-yl)-3-aryl/heteroaryl-5-methylpyrazoles

This report describes an efficient and practical approach for regioselective synthesis of 1-(3′-substituted quinoxalin-2′-yl)-3- aryl/heteroaryl-5-methylpyrazoles (3a-j). Reaction of 2-chloro-3-substituted quinoxalines (1) with 3(5)-methyl-5(3)-aryl-1H-pyrazoles (2) in the presence of sodium hydride furnished the title compounds in excellent yields with good levels of regioselectivity. The present protocol is superior to the existing method, which yielded a mixture of regioisomeric pyrazoles (I, II) and triazolo[4,3-a]quinoxalines (III). Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.