1431374-76-3

Basic information

• Product Name: 2-(2-butyl-4-fluorophenyl)pyridine
• CAS NO: 1431374-76-3
• Molecular Weight: 229.297
• Mol File: 1431374-76-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-butyl-4-fluorophenyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-butyl-4-fluorophenyl)pyridine(1431374-76-3)
• EPA Substance Registry System: 2-(2-butyl-4-fluorophenyl)pyridine(1431374-76-3)

Safety Data

• Hazardous Substances Data: 1431374-76-3(Hazardous Substances Data)

Upstream product

• 391604-55-0 2-(2,4-difluorophenyl)pyridine 
• 109-04-6 2-bromo-pyridine 
• 693-04-9 butyl magnesium bromide 
• 144025-03-6 2,4-difluorophenylboronic acid 

Relevant articles and documents

Ligand-induced reactivity of β-diketiminate magnesium complexes for regioselective functionalization of fluoroarenes: Via C-H or C-F bond activations

Using β-diketiminate Mg(ii) complexes containing either alkyl, aryl or amide groups, the regioselective functionalization of a wide range of fluoroarenes is accomplished but in uniquely different ways. Overcoming common limitations of traditional s-block bases, kinetically activated [(DippNacnac)Mg(TMP)] (1) deprotonates these molecules at room temperature, trapping sensitive fluoroaryl anions that can then engage in Negishi cross-coupling; whereas [(DippNacnac)Mg(R)THF] (R = nBu, Ph, benzofuryl) have proved to be effective reagents for C-F bond alkylation/arylation via pyridine directed C-F bond cleavage.