1431968-87-4

Basic information

• Product Name: 2-benzyl-5-thioxo-5,6-dihydro-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7(4H)-one
• Synonyms: 2-benzyl-5-thioxo-5,6-dihydro-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7(4H)-one
• CAS NO: 1431968-87-4
• Molecular Weight: 259.291
• Mol File: 1431968-87-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-benzyl-5-thioxo-5,6-dihydro-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzyl-5-thioxo-5,6-dihydro-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7(4H)-one(1431968-87-4)
• EPA Substance Registry System: 2-benzyl-5-thioxo-5,6-dihydro-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7(4H)-one(1431968-87-4)

Safety Data

• Hazardous Substances Data: 1431968-87-4(Hazardous Substances Data)

Upstream product

• 103-80-0 phenylacetyl chloride 
• 937-39-3 2-phenylacetylhydrazine 
• 591246-80-9 C₉H₁₂N₄O 
• 1431968-97-6 C₁₃H₁₅N₅O₂S 
• 22819-07-4 3-benzyl-1H-1,2,4-triazol-5-amine 

Relevant articles and documents

A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5] triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities

Thirty-three 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues were designed and synthesized which contained different substituents at meta- and/or para-positions of 2-phenyl or 2-benzyl ring attached to the fused ring structure. Th

Synthesis, in vitro evaluation of thymidine phosphorylase inhibitory activity, and in silico study of 1,3,5-triazin-2,4-dione and its fused analogues

Based on structural similarities with the reference compounds, a series of 1,3,5-triazin-2,4-dione and their fused analogues was designed, synthesized and their in vitro thymidine phosphorylase inhibitory potential was evaluated. The monocyclic analogues