143358-20-7Relevant articles and documents
INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR
-
Page/Page column 165-166, (2021/10/11)
Chromanone compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with the inhibition of antigen presentation by HLA-DR.
Development of 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs) from natural isoflavones, a new class of fluorescent scaffolds for biological imaging
Miao, Jianzhuang,Cui, Huaqing,Jin, Jing,Lai, Fangfang,Wen, Hui,Zhang, Xiang,Ruda, Gian Filippo,Chen, Xiaoguang,Yin, Dali
, p. 881 - 884 (2015/02/19)
Starting from 7-hydroxyisoflavones, we developed a new class of fluorescent scaffolds, 3-alkyl-6-methoxy-7-hydroxy-chromones (AMHCs, MW ~ 205.19, λab ~ 350 nm, λem ~ 450 nm) via a trial and error process. AMHCs have the advantages of being a small molecular moiety, having strong fluorescence in basic buffers, reasonable solubility and stability, non-toxicity, and are conveniently linked to pharmacophores. AMHCs were successfully used in fluorescence microscopy imaging of cells and tissues. This journal is
A simple synthesis of hydroxyisoflavanones
Gouda,Grover
, p. 142 - 144 (2007/10/03)
The isoflavanoids 7-hydroxyisoflavanone 4a, 7-hydroxy-3′, 4′-dimethoxyisoflavanone 4b, 5, 7-dihydroxy-3′, 4′-dimethoxyisoflavanone 4c, 5, 7-dihydroxy-2′-methoxyisoflavanone 4d, 5, 7-dihydroxy-3′, 4′-dimethoxyisoflavanone 4e and 5, 7-dihydroxy-4′-methoxyisoflavanone 4f have been conveniently prepared by using paraforomaldehyde and diethylamine as a base.