143359-20-0

Basic information

• Product Name: N-(7-guanyl)ethyl-N-chloroethyl-p-aminophenylbutyric acid
• Synonyms: N-(7-guanyl)ethyl-N-chloroethyl-p-aminophenylbutyric acid
• CAS NO: 143359-20-0
• Molecular Weight: 418.883
• Mol File: 143359-20-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(7-guanyl)ethyl-N-chloroethyl-p-aminophenylbutyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-(7-guanyl)ethyl-N-chloroethyl-p-aminophenylbutyric acid(143359-20-0)
• EPA Substance Registry System: N-(7-guanyl)ethyl-N-chloroethyl-p-aminophenylbutyric acid(143359-20-0)

Safety Data

• Hazardous Substances Data: 143359-20-0(Hazardous Substances Data)

Upstream product

• 961-07-9 2'-Deoxyguanosine 
• 305-03-3 chlorambucil 

Downstream Products

• 143359-21-1 N-(7-guanylethyl)-N-hydroxyethyl-p-aminophenylbutyric acid 

Relevant articles and documents

Simplified method for the isolation of thermally labile drug-DNA adducts: Characterization of chlorambucil and carzinophilin/azinomycin B alkylation products

A simple and rapid method has been developed for the isolation of thermally labile DNA alkylation products. Use of calf thymus DNA in combination with size exclusion filtration provides good yields >40% of chlorambucil-guanine adducts. Application of this