1433778-32-5

Basic information

• Product Name: (3R,5R,8R,9S,10R,12S,13R,14S,17R)-10,13-dimethyl-17-((2R,6S)-5-oxo-6-phenylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,12-diyldiacetate
• CAS NO: 1433778-32-5
• Molecular Weight: 564.806
• Mol File: 1433778-32-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,5R,8R,9S,10R,12S,13R,14S,17R)-10,13-dimethyl-17-((2R,6S)-5-oxo-6-phenylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,12-diyldiacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5R,8R,9S,10R,12S,13R,14S,17R)-10,13-dimethyl-17-((2R,6S)-5-oxo-6-phenylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,12-diyldiacetate(1433778-32-5)
• EPA Substance Registry System: (3R,5R,8R,9S,10R,12S,13R,14S,17R)-10,13-dimethyl-17-((2R,6S)-5-oxo-6-phenylheptan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene-3,12-diyldiacetate(1433778-32-5)

Safety Data

• Hazardous Substances Data: 1433778-32-5(Hazardous Substances Data)

Upstream product

• 672-65-1 (1-chloroethyl)benzene 
• 57610-90-9 Deoxycholic acid chloride 3,12-diacetate 
• 33628-48-7 deoxycholic acid 3,12-diacetate 
• 98-85-1 1-Phenylethanol 

Relevant articles and documents

Catalytic asymmetric reductive acyl cross-coupling: Synthesis of enantioenriched acyclic α,α-disubstituted ketones

The first enantioselective Ni-catalyzed reductive acyl cross-coupling has been developed. Treatment of acid chlorides and racemic secondary benzyl chlorides with a NiII/bis(oxazoline) catalyst in the presence of Mn0 as a stoichiometric reductant generates acyclic α,α-disubstituted ketones in good yields and high enantioselectivity without requiring stoichiometric chiral auxiliaries or pregeneration of organometallic reagents. The mild, base-free reaction conditions are tolerant of a variety of functional groups on both coupling partners.