143467-21-4

Basic information

• Product Name: 1-acetyl-3-cyanoadamantane
• Synonyms: 1-acetyl-3-cyanoadamantane
• CAS NO: 143467-21-4
• Molecular Weight: 203.284
• Mol File: 143467-21-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-acetyl-3-cyanoadamantane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetyl-3-cyanoadamantane(143467-21-4)
• EPA Substance Registry System: 1-acetyl-3-cyanoadamantane(143467-21-4)

Safety Data

• Hazardous Substances Data: 143467-21-4(Hazardous Substances Data)

Upstream product

• 62472-38-2 adamantane-1,3-dicarbonitrile 
• 74-88-4 methyl iodide 

Relevant articles and documents

Reactions of Grignard reagents with 1,3-dicyanoadamantane

Reactions of Grignard reagents RMgX (R = Me, Et, Pr, Bu; X = Br, I) with 1,3-dicyanoadamantane (1) were studied. Optimum conditions for the synthesis of monoaddition products of Grignard reagents to compound 1 were established. The first stage of the reaction of cyanoadamantane 1 with MeMgBr was studied by the MNDO-PM3 method. According to calculations, the more preferable reaction mechanism involves formation of a six-membered cyclic intermediate containing two Mg atoms, two C atoms, and one Br and one N atom.