1435387-44-2

Basic information

• Product Name: N-(2-nitro-5-(2-oxo-2,3-dihydrothiazol-4-yl)phenyl)-2-phenylacetamide
• Synonyms: N-(2-nitro-5-(2-oxo-2,3-dihydrothiazol-4-yl)phenyl)-2-phenylacetamide
• CAS NO: 1435387-44-2
• Molecular Weight: 355.374
• Mol File: 1435387-44-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-nitro-5-(2-oxo-2,3-dihydrothiazol-4-yl)phenyl)-2-phenylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-nitro-5-(2-oxo-2,3-dihydrothiazol-4-yl)phenyl)-2-phenylacetamide(1435387-44-2)
• EPA Substance Registry System: N-(2-nitro-5-(2-oxo-2,3-dihydrothiazol-4-yl)phenyl)-2-phenylacetamide(1435387-44-2)

Safety Data

• Hazardous Substances Data: 1435387-44-2(Hazardous Substances Data)

Upstream product

• 7463-31-2 3-Acetamidoacetophenone 
• 30095-56-8 1-(3-Acetylaminophenyl)-2-bromoethanone 
• 1435387-28-2 N-(5-(2-bromoacetyl)-2-nitrophenyl)acetamide 
• 1435387-36-2 4-(3-amino-4-nitrophenyl)thiazol-2(3H)-one 
• 103-80-0 phenylacetyl chloride 
• 99-03-6 1-(3-aminophenyl)ethanone 

Downstream Products

• 1435387-76-0 N-(2-amino-5-(2-oxo-2,3-dihydrothiazol-4-yl)phenyl)-2-phenylacetamide 
• 1435386-06-3 C₂₁H₁₇N₃O₄S₃ 

Relevant articles and documents

A kind of two-thiazoline ketone compounds and pharmaceutical compositions thereof and use thereof (by machine translation)

The invention provides general formula (I) indicated by the thiazoline ketone compounds and pharmaceutical compositions thereof and use thereof. The compounds can be combined with the bromodomain domain of the protein, thereby adjusting the downstream signal path, to play a particular function, can be used for treating the relevant domain protein in the bromodomain of various diseases. Such compounds can be interference has Brd4 bromodomain domain with the acetylated histone binding, and then lower the oncogene c - the ventilating cabins and its related target gene transcription, so that it may be effective for treating the tumor. (by machine translation)