143564-16-3

Basic information

• Product Name: (S)-4-(3,4,5-Trimethoxy-benzyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one
• Synonyms: (S)-4-(3,4,5-Trimethoxy-benzyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one
• CAS NO: 143564-16-3
• Molecular Weight: 444.482
• Mol File: 143564-16-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-(3,4,5-Trimethoxy-benzyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(3,4,5-Trimethoxy-benzyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(143564-16-3)
• EPA Substance Registry System: (S)-4-(3,4,5-Trimethoxy-benzyl)-3-[1-(3,4,5-trimethoxy-phenyl)-meth-(E)-ylidene]-dihydro-furan-2-one(143564-16-3)

Safety Data

• Hazardous Substances Data: 143564-16-3(Hazardous Substances Data)

Upstream product

• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 143616-19-7 (S)-dihydro-4-(3,4,5-trimethoxybenzyl)furan-2(3H)-one 
• 76763-88-7 (R)-dihydro-4-(3,4,5-trimethoxybenzyl)furan-2(3H)-one 

Downstream Products

• 7432-28-2 schizandrin 
• 7432-28-2 isoschizandrin 

Relevant articles and documents

Synthesis of optically pure gomisin A and schizandrin: The first total synthesis of gomisin A and schizandrin having naturally occurring configurations

The total synthesis of gomisin A and schizandrin having natural configurations were accomplished for the first time. The key feature of these syntheses is a highly efficient intramolecular oxidative coupling of the intermediates 9 and 21, which can be obtained as both enantiomers in optically pure forms. The manipulation of the lactone moieties of 7 and 22 afforded natural enantiomers of schizandrin and gomisin A.