1435914-39-8

Basic information

• Product Name: N-{2,2-dichloro-1-[(5-chloro-2-pyridinyl)amino]-2-phenylethyl}-4-chlorobenzenesulfonamide
• Synonyms: N-{2,2-dichloro-1-[(5-chloro-2-pyridinyl)amino]-2-phenylethyl}-4-chlorobenzenesulfonamide
• CAS NO: 1435914-39-8
• Molecular Weight: 491.225
• Mol File: 1435914-39-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-{2,2-dichloro-1-[(5-chloro-2-pyridinyl)amino]-2-phenylethyl}-4-chlorobenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{2,2-dichloro-1-[(5-chloro-2-pyridinyl)amino]-2-phenylethyl}-4-chlorobenzenesulfonamide(1435914-39-8)
• EPA Substance Registry System: N-{2,2-dichloro-1-[(5-chloro-2-pyridinyl)amino]-2-phenylethyl}-4-chlorobenzenesulfonamide(1435914-39-8)

Safety Data

• Hazardous Substances Data: 1435914-39-8(Hazardous Substances Data)

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 98416-35-4 N-(2-benzene-2,2-dichloroethylidene)-4-chlorobenzenesulfonamide 

Relevant articles and documents

One-pot synthesis of N-(imidazo[1,2-a]pyridin-3-yl)-and N-(imidazo[2,1-b][1,3]thiazol-5-yl)sulfonamides

The reaction of 2-aminopyridines or 2-aminothiazole with N-(2,2-dichloro-2-phenylethylidene)arensulfonamides affords the corresponding products of nucleophilic addition to the azomethine group, N-[2,2-dichloro-2- phenyl-1-(heterylamino)ethyl]sulfonamides, in good yields. The latter are easily cyclized to (imidazo[1,2-a]pyridin-3-yl)sulfonamides and (imidazo[2,1-b] thiazol-5-yl)sulfonamides in the presence of alkali, whereas the expected isomeric (imidazo[1,2-a]pyridin-2-yl)sulfonamides and (imidazo[2,1-b]thiazol-6- yl)sulfonamides are not formed. A one-pot two-stage method for the synthesis of target heterocyclic compounds without the isolation of intermediates has been developed. A tentative mechanism of the formation of annulated heterocyclic derivatives has been proposed.