1436417-40-1Relevant articles and documents
Total synthesis of dictyodendrins B and e
Liang, Jingjing,Hu, Weimin,Tao, Pengyu,Jia, Yanxing
, p. 5810 - 5815 (2013)
The concise synthesis of the novel telomerase inhibitors dictyodendrins B and E was completed in only 9 and 11 steps (longest linear sequence). The highly convergent strategy employed a palladium-catalyzed Larock indole synthesis and a palladium-mediated one-pot consecutive Buchwald-Hartwig amination/C-H activation reaction as key steps. The present synthesis exhibits respectable levels of atom-, redox-, and step-economy.