143642-68-6

Basic information

• Product Name: (R)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-3-(3-nitro-pyridin-2-yldisulfanyl)-propionic acid
• CAS NO: 143642-68-6
• Molecular Weight: 699.766
• Mol File: 143642-68-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-3-(3-nitro-pyridin-2-yldisulfanyl)-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-3-(3-nitro-pyridin-2-yldisulfanyl)-propionic acid(143642-68-6)
• EPA Substance Registry System: (R)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-acetylamino}-acetylamino)-3-phenyl-propionylamino]-3-(3-nitro-pyridin-2-yldisulfanyl)-propionic acid(143642-68-6)

Safety Data

• Hazardous Substances Data: 143642-68-6(Hazardous Substances Data)

Upstream product

• 4530-20-5 BOC-glycine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 76880-29-0 N-α-tert-butoxycarbonyl-S-(3-nitro-2-pyridylthio)-L-cysteine 
• 47689-67-8 (S)-3-[4-(2-Bromo-benzyloxycarbonyloxy)-phenyl]-2-tert-butoxycarbonylamino-propionic acid 

Relevant articles and documents

Design and Synthesis of Highly Specific and Selective Enkephalin Analog Containing S-Npys-Cysteine for &δ Opioid Receptors

Enkephalin analogs containing S-(3-nitro-2-pyridinesulfenyl)cysteine at positions of 1, 5, or 6 were synthesized for searching possible thiol groups in the opioid receptors.In the radio-ligand receptor assay and biological assays, 2, Leu5>enkephalyl-Cys(Npys)6 exhibited a very high affinity and selectivity for δ over μ receptors, and its covalent attachment to δ receptors through the disulfide bonding was evidenced.