143693-24-7 Usage
Description
(R)-2-Hydroxybutyl tosylate, also known as (2S)-2-hydroxybutyl 4-methylbenzenesulfonate, is a tosylate ester derived from toluenesulfonic acid. It has the chemical formula C11H16O4S and is characterized by its ability to protect hydroxyl groups in alcohol molecules during organic synthesis.
Uses
Used in Pharmaceutical Industry:
(R)-2-Hydroxybutyl tosylate is used as a reagent for the protection of hydroxyl groups in alcohol molecules, which is crucial in the preparation of various pharmaceutical intermediates. Its ability to shield hydroxyl groups allows for selective reactions and the synthesis of complex molecules with precision.
Used in Agrochemical Industry:
In the agrochemical industry, (R)-2-Hydroxybutyl tosylate serves as a reagent for the synthesis of various agrochemicals. Its role in protecting hydroxyl groups is essential for the development of effective and targeted compounds for agricultural applications.
Used in Synthetic Chemistry:
(R)-2-Hydroxybutyl tosylate is also used as a versatile and valuable tool in synthetic chemistry. The tosylate group can be easily removed under mild conditions, making it an ideal choice for protecting hydroxyl groups during complex chemical reactions. This feature allows chemists to control the reactivity of alcohols and design synthetic pathways with greater ease and efficiency.
Check Digit Verification of cas no
The CAS Registry Mumber 143693-24-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,6,9 and 3 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 143693-24:
(8*1)+(7*4)+(6*3)+(5*6)+(4*9)+(3*3)+(2*2)+(1*4)=137
137 % 10 = 7
So 143693-24-7 is a valid CAS Registry Number.
143693-24-7Relevant articles and documents
PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF
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Page/Page column 342-343, (2021/06/26)
Provided herein are compounds, compositions, and methods useful for inhibiting protein tyrosine phosphatase, e.g, protein tyrosine phosphatase non-receptor type 2 (PTPN2) and/or protein tyrosine phosphatase non-receptor type 1 (PTPN1), and for treating related diseases, disorders and conditions favorably responsive to PTPN1 or PTPN2 inhibitor treatment, e.g, a cancer or a metabolic disease.
4-hydroxy-6-alkyl-2-pyrones as nucleophilic coupling partners in Mitsunobu reactions and oxa-Michael additions
Burns, Michael J.,Ronson, Thomas O.,Taylor, Richard J. K.,Fairlamb, Ian J. S.
supporting information, p. 1159 - 1165 (2014/06/09)
Two mild and efficient strategies have been developed for the O-functionalisation of 4-hydroxy-6-alkyl-2-pyrones, by using them as nucleophilic partners in oxa-Michael additions and the Mitsunobu reaction. The reactions proceed in moderate to excellent yields on a range of substrates containing useful functionality. The reactions serve as practical and valuable synthetic methods to construct complex 2-pyronyl ethers, which are found embedded in a number of natural products.
Synthesis of 4-n-alkyl-2-amino-3-thiophenecarboxylates
Noe,Buchstaller,Siebert
, p. 833 - 836 (2007/10/03)
A modification of the Gewald reaction is presented, which renders 4-n-alkyl substituted 2-aminothiophene derivatives 9 accessible, which bear no substituent at position 5. The three step procedure involves monotosylation of diols 2, oxidation of the secon
