1437303-18-8

Basic information

• Product Name: 3β-phthaloyl-urs-12-en-28-carboxamide
• Synonyms: 3β-phthaloyl-urs-12-en-28-carboxamide
• CAS NO: 1437303-18-8
• Molecular Weight: 603.843
• Mol File: 1437303-18-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3β-phthaloyl-urs-12-en-28-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-phthaloyl-urs-12-en-28-carboxamide(1437303-18-8)
• EPA Substance Registry System: 3β-phthaloyl-urs-12-en-28-carboxamide(1437303-18-8)

Safety Data

• Hazardous Substances Data: 1437303-18-8(Hazardous Substances Data)

Upstream product

• 54717-94-1 3β-acetoxy-urs-12-ene-28-oyl chloride 
• 915-79-7 (3β)-3-acetoxy-urs-12-en-28-carboxylic acid 
• 77-52-1 ursolic acid 
• 85-44-9 phthalic anhydride 
• 107398-01-6 3β-Acetoxy-18β-H-urs-12-en-28-carboxamide 

Relevant articles and documents

Synthesis and cytotoxic activity of ursolic acid derivatives

Fourteen ursolic acid derivatives, among them four novel compounds, were synthesized by modification either at the C-3, C-28 or both positions. The cytotoxic activity of the obtained derivatives was evaluated against the four human cancer cell lines KB (human mouth epidermal carcinoma), HepG2 (human hepatocellular carcinoma), MCF7 (human breast carcinoma) and Lu (human lung carcinoma). As the result, compounds 7 and 8 were from two to three times more active than ursolic acid on all four tested cell lines. This is the first report on cytotoxic effects of the synthetized ursolic acid derivatives 4, 8, and 10-15.