14376-92-2Relevant articles and documents
Aminoenylesters. I. A new synthesis of 1,2,3,4-tetrahydropyrimidines by heterocyclic annelation reactions of aminoenylesters with primary amines and acetaldehyde
Koike, Takeshi,Tanabe, Mituharu,Takeuchi, Naoki,Tobinaga, Seisho
, p. 1117 - 1119 (1997)
The reactions of aminoenylesters 3, which were prepared by the reactions of methyl propiolate (1) and primary amines 2, with primary amines 2 and acetaldehyde afforded 1,2,3,4-tetrahydropyrimidines 4. This provides a new heterocyclic annelation reaction.
Lewis acid-promoted cascade reaction of primary amine, 2-butynedioate, and propargylic alcohol: A convenient approach to 1,2-dihydropyridines and 1H-pyrrolo[3,4-b]pyridine-5,7(2H,6H)-diones
Yin, Guangwei,Zhu, Yuanxun,Wang, Ningning,Lu, Ping,Wang, Yanguang
, p. 8353 - 8359 (2013/09/02)
1,2-Dihydropyridine-5,6-dicarboxylates were efficiently constructed through a cascade reaction of primary amine, 2-butynedioate and propargylic alcohol in the presence of Lewis acid under mild conditions. As exceptional, 1H-pyrrolo[3,4-b]pyridine-5,7(2H,6
A short synthesis of (±)-cytisine
Botuha, Candice,Galley, Carl M. S.,Gallagher, Timothy
, p. 1825 - 1826 (2007/10/03)
The synthesis of racemic cytisine 1 has been completed using (i) N-selective alkylation of 6-bromopyridone with bromide 6 and (ii) Pd(o) mediated intramolecular a-arylation of lactam 8 as key steps to achieve rapid assembly of the tricyclic core skeleton of the lupin alkaloids.
