14385-54-7

Basic information

• Product Name: 2-phenylnaphtho[2,1-b]furan
• Synonyms: 2-phenylnaphtho[2,1-b]furan
• CAS NO: 14385-54-7
• Molecular Formula: C₁₈H₁₂O
• Molecular Weight: 244.28728
• Mol File: 14385-54-7.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-phenylnaphtho[2,1-b]furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylnaphtho[2,1-b]furan(14385-54-7)
• EPA Substance Registry System: 2-phenylnaphtho[2,1-b]furan(14385-54-7)

Safety Data

• Hazardous Substances Data: 14385-54-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 183859-96-3 1-phenylethynyl-3,4-dihydronaphthalene-2-carboxaldehyde 
• 100-42-5 styrene 
• 573-97-7 1-bromo-2-naphthol 
• 947232-06-6 2-(β,β-dibromovinyl)-2-naphthol 
• 2996-92-1 phenyl trimethylsiloxane 
• 873-55-2 sodium benzenesulfonate 
• 135-19-3 β-naphthol 
• 536-74-3 phenylacetylene 
• 1449-46-3 benzyltriphenylphosphonium bromide 
• 100-39-0 benzyl bromide 
• 100-51-6 benzyl alcohol 
• 591-50-4 iodobenzene 
• 117516-71-9 [2]naphthyloxy-acetaldehyde diethylacetal 

Downstream Products

• 91388-11-3 formyl-1 phenyl-2 naphto<2,1-b>furanne 
• 91388-12-4 formyl-5 phenyl-2 naphto<2,1-b>furanne 
• 91388-13-5 acetyl-5 phenyl-2 naphto<2,1-b>furanne 

Relevant articles and documents

Selectfluor-Mediated Stereoselective [1 + 1 + 4 + 4] Dimerization of Styrylnaphthols

Stereoselective [1 + 1 + 4 + 4] dimerization of 1-styrylnaphthols has been developed by using Selectfluor as the oxidant for the first time. The reaction was compatible with various functional groups, giving a class of ethanodinaphtho[b,f][1,5]dioxocines

Acid-catalyzed cleavage of C-C bonds enables atropaldehyde acetals as masked C2 electrophiles for organic synthesis

Acid-catalyzed tandem reactions of atropaldehyde acetals were established for the synthesis of three important molecules, 2,2-disubstituted indolin-3-ones, naphthofurans and stilbenes. The synthesis was realized using novel reaction cascades, which involved the same two initial steps: (i) SN2′ substitution, in which the atropaldehyde acted as an electrophile; and (ii) oxidative cleavage of the carbon-carbon bond of the generated phenylacetaldehyde-type products. Compared with literature methods, the present protocol not only avoided the use of expensive noble metal catalysts, but also enabled a simple operation.

Synthesis and biological evaluation of 2-arylbenzofuran derivatives as potential anti-Alzheimer’s disease agents

Alzheimer's disease (AD) is a type of progressive dementia caused by degeneration of the nervous system. A single target drug usually does not work well. Therefore, multi-target drugs are designed and developed so that one drug can specifically bind to mu