143866-70-0

Basic information

• Product Name: Piperidine, 4-(4-chlorophenyl)-1-(phenylmethyl)-
• CAS NO: 143866-70-0
• Molecular Formula: C18H20ClN
• Molecular Weight: 285.817
• Mol File: 143866-70-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Piperidine, 4-(4-chlorophenyl)-1-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 4-(4-chlorophenyl)-1-(phenylmethyl)-(143866-70-0)
• EPA Substance Registry System: Piperidine, 4-(4-chlorophenyl)-1-(phenylmethyl)-(143866-70-0)

Safety Data

• Hazardous Substances Data: 143866-70-0(Hazardous Substances Data)

Upstream product

• 231958-20-6 4-(4-chlorophenyl)-1,2,3,6-tetrahydro-1-(phenylmethyl)-pyridine 
• 56108-25-9 N-benzyl-4-(4-chlorophenyl)-4-hydroxypiperidin 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 100-39-0 benzyl bromide 
• 41979-39-9 4-piperidone hydrochloride 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 26905-02-2 4-(4-chlorophenyl)piperidine 

Relevant articles and documents

Pharmacophore-based discovery, synthesis, and biological evaluation of 4-phenyl-1-arylalkyl piperidines as dopamine transporter inhibitors

Pharmacophore-based discovery, synthesis, and structure-activity relationship (SAR) of a series of 4-phenyl-1-arylalkyl piperidines are disclosed. These compounds have been evaluated for their ability to inhibit reuptake of dopamine (DA) into striatal nerve endings (synaptosomes). The lead compound 5 and the most potent analogue 43 were found to have significant functional antagonism.