143949-72-8 Usage
Description
3-(1H-Benzoimidazol-2-yl)-Propionic Acid Hydrazide is a chemical compound that belongs to the class of propionic acid derivatives and features a benzoimidazole ring. It has been studied for its potential pharmaceutical applications, including as an antitumor agent and an antioxidant. Additionally, it has shown promise as a therapeutic agent for neurological disorders due to its ability to cross the blood-brain barrier. Further research is necessary to fully explore its pharmacological properties and potential uses.
Uses
Used in Pharmaceutical Industry:
3-(1H-Benzoimidazol-2-yl)-Propionic Acid Hydrazide is used as an antitumor agent for its potential to combat cancer cells. It is being investigated for its ability to inhibit tumor growth and progression, making it a candidate for cancer treatment.
Used in Antioxidant Applications:
As an antioxidant, 3-(1H-Benzoimidazol-2-yl)-Propionic Acid Hydrazide is utilized to counteract oxidative stress and protect cells from damage caused by reactive oxygen species, which can contribute to various diseases and aging.
Used in Neurological Disorder Treatment:
3-(1H-Benzoimidazol-2-yl)-Propionic Acid Hydrazide is used as a potential therapeutic agent for the treatment of neurological disorders. Its ability to cross the blood-brain barrier makes it a candidate for drugs targeting the central nervous system, potentially aiding in the treatment of conditions such as Alzheimer's, Parkinson's, and other neurodegenerative diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 143949-72-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,9,4 and 9 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 143949-72:
(8*1)+(7*4)+(6*3)+(5*9)+(4*4)+(3*9)+(2*7)+(1*2)=158
158 % 10 = 8
So 143949-72-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H12N4O/c11-14-10(15)6-5-9-12-7-3-1-2-4-8(7)13-9/h1-4H,5-6,11H2,(H,12,13)(H,14,15)
143949-72-8Relevant articles and documents
Synthesis of some hydroxamic acid derivatives of benzimidazole and their antibacterial and antifungal activities
Gunes,Cosar
, p. 1045 - 1048 (2007/10/02)
A number of 1H-benzimidazole-2-propanoic acid derivatives have been synthesized by Phillips method, and their antibacterial and antifungal activities have been tested. The chemical structures of the synthesized compounds were elucidated by spectroscopic (IR, NMR, mass) and elementary analysis. Investigation of antimicrobial activity of the compounds was done by agar dilution technique using bacteria (Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Mycobacterium smegmatis ATCC 607) and yeast-like fungi (Candida albicans, Candida tropicalis, Candida pseudotropicalis, Candida kruzei, Candida globrata). Among the compounds tested N-hydroxy-3-(1H-benzimidazol-2-yl)-propionamide (Compound 6) showed considerable activity against both Candida albicans and Candida tropicalis.
