143951-58-0

Basic information

• Product Name: {(S)-1-[2-((3R,11bR)-9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-ethyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-(2-phenoxy-phenyl)-methanone
• CAS NO: 143951-58-0
• Molecular Weight: 662.826
• Mol File: 143951-58-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(S)-1-[2-((3R,11bR)-9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-ethyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-(2-phenoxy-phenyl)-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-1-[2-((3R,11bR)-9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-ethyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-(2-phenoxy-phenyl)-methanone(143951-58-0)
• EPA Substance Registry System: {(S)-1-[2-((3R,11bR)-9,10-Dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-ethyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl}-(2-phenoxy-phenyl)-methanone(143951-58-0)

Safety Data

• Hazardous Substances Data: 143951-58-0(Hazardous Substances Data)

Upstream product

• 143951-54-6 trans-N-<2-(3,4-dimethoxyphenyl)ethyl>-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-3-propanamide 
• 143951-56-8 trans-3-<2-(6,7-dimethoxy-3,4-dihydro-1-isoquinolinyl)ethyl>-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine 
• 143951-47-7 methyl trans-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-4-oxo-2H-benzoquinolizine-3-propanoate 
• 143951-46-6 3-((3S,11bS)-9,10-Dimethoxy-4-oxo-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-propionic acid 
• 143951-46-6 3-(9,10-Dimethoxy-4-oxo-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-3-yl)-propionic acid 
• 143951-49-9 methyl trans-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-3-propanoate 
• 143951-44-4 ethyl 3-ethoxycarbonyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-4-oxo-2H-benzoquinolizine-3-propanoate 
• 143951-45-5 3-carboxy-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzoquinolizine-3-propanoic acid 
• 143951-60-4 diethyl 2-ethylmalonate 
• 143951-61-5 diethyl 2-(6,7-dimethoxy-3,4-dihydro-1-isoquinolinyl)ethylmalonate 
• 143951-43-3 ethyl 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-4-oxo-2H-benzoquinolizine-3-carboxylate 
• 143951-62-6 4,4-bis(ethoxycarbonyl)butanoyl chloride 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 40501-36-8 2-phenoxybenzoyl chloride 

Downstream Products

• 143951-59-1 (3R,11bR)-3-{2-[(S)-6,7-Dimethoxy-2-(2-phenoxy-benzyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-ethyl}-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline 
• 143951-59-1 (3R,11bS)-3-{2-[(S)-6,7-Dimethoxy-2-(2-phenoxy-benzyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-ethyl}-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline 
• 143951-59-1 (3S,11bR)-3-{2-[(S)-6,7-Dimethoxy-2-(2-phenoxy-benzyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-ethyl}-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline 
• 143951-59-1 (3S,11bS)-3-{2-[(S)-6,7-Dimethoxy-2-(2-phenoxy-benzyl)-1,2,3,4-tetrahydro-isoquinolin-1-yl]-ethyl}-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinoline 

Relevant articles and documents

Synthesis of C-nor emetine pyman

The four stereoisomers of C-nor emetine Pyman (2) were synthesized and isolated as their hydrobromides (2a-d·2HBr). Reduction of 3,11b-trans dehydro C-nor emetine Pyman (13a) gave an inseparable mixture of 2a and 2b. They were converted into the correspon