1439607-59-6

Basic information

• Product Name: 3′-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5′-O-(4,4′-dimethoxytrityl)-N²-(2-((9-fluorenylmethyloxycarbonyl)amino)propyl) 2′-deoxy-5-methylisocytidine
• CAS NO: 1439607-59-6
• Molecular Weight: 1023.18
• Mol File: 1439607-59-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3′-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5′-O-(4,4′-dimethoxytrityl)-N²-(2-((9-fluorenylmethyloxycarbonyl)amino)propyl) 2′-deoxy-5-methylisocytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3′-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5′-O-(4,4′-dimethoxytrityl)-N²-(2-((9-fluorenylmethyloxycarbonyl)amino)propyl) 2′-deoxy-5-methylisocytidine(1439607-59-6)
• EPA Substance Registry System: 3′-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5′-O-(4,4′-dimethoxytrityl)-N²-(2-((9-fluorenylmethyloxycarbonyl)amino)propyl) 2′-deoxy-5-methylisocytidine(1439607-59-6)

Safety Data

• Hazardous Substances Data: 1439607-59-6(Hazardous Substances Data)

Upstream product

• 1439607-44-9 C₁₂H₂₀N₄O₄ 
• 1439607-41-6 N²-[2-[(9-fluorenylmethyloxycarbonyl)amino]ethyl]-2′-deoxy-5-methylisocytidine 
• 15425-09-9 3,5'-cyclo-2'-deoxyguanosine 
• 1449676-22-5 C₄₈H₄₈N₄O₈ 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 

Relevant articles and documents

N-(Guanidinoethyl)-2′-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site for the formation of anti-parallel triplexes

The development of novel nucleoside analogues for the formation of triplex DNA containing pyrimidine-purine inversion sites has been a challenging field. In this paper, we describe the design and synthesis of non-natural nucleoside analogues, N-substituted-2′-deoxy-5-methylisocytidine derivatives, and their evaluation for triplex formation. It has been shown that N-(guanidinoethyl)-2′-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site and potentiates the formation of anti-parallel triplexes. This journal is The Royal Society of Chemistry 2013.