1439936-30-7

Basic information

• Product Name: N-(4-{4-[(5-methoxypyrazin-2-yl)oxy]-2,6-dimethylphenyl}thiazol-2-yl)isonicotinamide
• Synonyms: N-(4-{4-[(5-methoxypyrazin-2-yl)oxy]-2,6-dimethylphenyl}thiazol-2-yl)isonicotinamide
• CAS NO: 1439936-30-7
• Molecular Weight: 433.491
• Mol File: 1439936-30-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-{4-[(5-methoxypyrazin-2-yl)oxy]-2,6-dimethylphenyl}thiazol-2-yl)isonicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-{4-[(5-methoxypyrazin-2-yl)oxy]-2,6-dimethylphenyl}thiazol-2-yl)isonicotinamide(1439936-30-7)
• EPA Substance Registry System: N-(4-{4-[(5-methoxypyrazin-2-yl)oxy]-2,6-dimethylphenyl}thiazol-2-yl)isonicotinamide(1439936-30-7)

Safety Data

• Hazardous Substances Data: 1439936-30-7(Hazardous Substances Data)

Upstream product

• 118738-91-3 1-(4-iodo-2,6-dimethylphenyl)ethanone 
• 143250-10-6 2-bromo-5-methoxypyrazine 
• 1439936-32-9 2-bromo-1-{4-((5-methoxypyrazin-2-yl)oxy)-2,6-dimethylphenyl}ethanone 
• 1439936-31-8 1-{4-((5-methoxypyrazin-2-yl)oxy)-2,6-dimethylphenyl}ethanone 
• 91060-92-3 1-(4-hydroxy-2,6-dimethylphenyl)ethanone 
• 1439936-33-0 4-{4-((5-methoxypyrazin-2-yl)oxy)-2,6-dimethylphenyl}thiazol-2-amine 
• 39178-35-3 isonicotinoyl chloride hydrochloride 

Relevant articles and documents

Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy

Highly expressed in cancer 1 (Hec1) plays an essential role in mitosis and is correlated with cancer formation, progression, and survival. Phosphorylation of Hec1 by Nek2 kinase is essential for its mitotic function, thus any disruption of Hec1/Nek2 prote