144035-34-7 Usage
Description
[2-(5-Cyano-1H-indol-3-yl)-ethyl]-carbaMic acid tert-butyl ester, also known as 5-Carboxamidotryptamine maleate (C338945) intermediate, is a chemical compound derived from the indole structure. It is characterized by the presence of a cyano group and a carbamic acid tert-butyl ester group, which contribute to its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
[2-(5-Cyano-1H-indol-3-yl)-ethyl]-carbaMic acid tert-butyl ester is used as an intermediate in the synthesis of 5-Carboxamidotryptamine maleate (C338945) for its agonistic effects on the 5-HT1 receptors. [2-(5-Cyano-1H-indol-3-yl)-ethyl]-carbaMic acid tert-butyl ester plays a crucial role in the development of new drugs targeting the serotonin system, which is involved in various physiological processes and disorders, such as mood regulation, anxiety, and depression.
Used in Chemical Synthesis:
In the field of chemical synthesis, [2-(5-Cyano-1H-indol-3-yl)-ethyl]-carbaMic acid tert-butyl ester can be utilized as a building block or a key intermediate for the creation of more complex molecules with potential applications in various industries, including pharmaceuticals, agrochemicals, and materials science. Its unique structural features make it a valuable component in the design and synthesis of novel compounds with specific biological activities or material properties.
Check Digit Verification of cas no
The CAS Registry Mumber 144035-34-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,0,3 and 5 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 144035-34:
(8*1)+(7*4)+(6*4)+(5*0)+(4*3)+(3*5)+(2*3)+(1*4)=97
97 % 10 = 7
So 144035-34-7 is a valid CAS Registry Number.
144035-34-7Relevant articles and documents
Methiodide Approach to the Synthesis of 3--5--1H-indole and Analogues
Castro, Jose L.,Matassa, Victor G.
, p. 4705 - 4708 (1993)
Tryptamines 1, 2 and 3 have been synthesised in a convergent and efficient manner by reaction of a novel methiodide 4c with the anions of the cyclic sulphamides 5, 6 and 7 as the key step.
Fused imidazole and triazole derivatives as 5-HT1 receptor agonists
-
, (2008/06/13)
Compounds of formula (I) wherein F represents a Group of the formula (a) ; E represents a bond or a straight or branched alkylene chain containing from 1 to 4 carbon atoms; and the rest of the variables are defined in the specification are selective agoni
Triazole containing indole derivatives
-
, (2008/06/13)
A class of substituted imidazole, triazole and tetrazole derivatives are selective agonists of 5-HT 1 -like receptors and are therefore useful in the treatment of clinical conditions, in particular migraine and associated disorders, for which a selective agonist of these receptors is indicated.
