144062-63-5

Basic information

• Product Name: 1H-Pyrrole-2-carboxylic acid, 1-[4-(bromomethyl)phenyl]-, methyl ester
• CAS NO: 144062-63-5
• Molecular Formula: C13H12BrNO2
• Molecular Weight: 294.148
• Mol File: 144062-63-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2-carboxylic acid, 1-[4-(bromomethyl)phenyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2-carboxylic acid, 1-[4-(bromomethyl)phenyl]-, methyl ester(144062-63-5)
• EPA Substance Registry System: 1H-Pyrrole-2-carboxylic acid, 1-[4-(bromomethyl)phenyl]-, methyl ester(144062-63-5)

Safety Data

• Hazardous Substances Data: 144062-63-5(Hazardous Substances Data)

Usage

Molecular Structure

1H-Pyrrole-2-carboxylic acid, 1-[4-(bromomethyl)phenyl]-, methyl ester is a chemical compound that consists of a pyrrole ring with a carboxylic acid group attached to the 2-position, a methyl ester group, and a bromomethylphenyl group on the 1-position of the pyrrole ring.

Molecular Weight

The molecular weight of this compound is not provided in the material.

Biological Activity

Pyrrole derivatives, including this compound, are known for their diverse biological activities, making them useful in pharmaceutical research and drug discovery.

Versatile Reactivity

The compound's reactivity and structural properties make it suitable for use in the synthesis of various pharmaceuticals and agrochemicals.

Potential Applications

1H-Pyrrole-2-carboxylic acid, 1-[4-(bromomethyl)phenyl]-, methyl ester has potential applications in organic synthesis and the development of new materials.

Analysis and Study

This chemical has been analyzed and studied for its potential uses in drug discovery and the development of new materials.

Upstream product

• 35524-48-2 1-(4-methylphenyl)pyrrole-2-carbonitrile 
• 35524-50-6 1-(4-methylphenyl)-1H-pyrrole-2-carboxylic acid 
• 35524-53-9 1-p-tolyl-pyrrole-2-carbonyl chloride 
• 106-49-0 p-toluidine 
• 30186-38-0 1-(4-methylphenyl)-2-formyl-1H-pyrrole 
• 827-60-1 1-(4-methylphenyl)-1H-pyrrole 
• 144062-62-4 1-(4-methylphenyl)-1H-pyrrole-2-carboxylic acid methyl ester 

Downstream Products

• 942429-64-3 C₂₃H₂₁N₃O₄ 
• 942429-63-2 C₂₄H₂₃N₃O₄ 
• 942429-62-1 C₂₅H₂₅N₃O₄ 
• 942429-61-0 methyl 2-butyl-1-[[4-(2-carbomethoxy-1H-pyrrol-1-yl)phenyl]methyl]-1H-benzimidazole-7-carboxylate 
• 942429-57-4 C₂₆H₂₇N₃O₇ 
• 942429-60-9 C₂₃H₂₁N₃O₇ 
• 942429-59-6 C₂₄H₂₃N₃O₇ 
• 942429-58-5 C₂₅H₂₅N₃O₇ 
• 144062-64-6 methyl 1-<4-<(3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl>phenyl>-1H-pyrrole-2-carboxylate 
• 145062-02-8 methyl 1-<4-<<2-n-butyl-4-(hydroxymethyl)-5-chloroimidazolyl>methyl>phenyl>-1H-pyrrole-2-carboxylate 
• 145062-01-7 methyl 1-<4-<<2-n-butyl-4-chloro-5-(hydroxymethyl)imidazolyl>methyl>phenyl>-1H-pyrrole-2-carboxylate 

Relevant articles and documents

Nonpeptide angiotensin II antagonists: N-phenyl-1H-pyrrole derivatives are angiotensin II receptor antagonists

A series of 5-[1-[4-[(4,5-disubstituted-1H-imidazol-1-yl)methyl]- substituted]-1H-pyrrol-2-yl]-1H-tetrazoles and 5-[1-[4-[(3,5-dibutyl-1H- 1,2,4-triazol-1-yl)methyl]-substituted]-1H-pyrrol-2-yl]-1H-tetrazoles were investigated as novel AT1-sele

N-SUBSTITUTED N-(ALPHA-TRIAZOLYL-TOLUYL)PYRROLE COMPOUNDS AND USE FOR TREATMENT OF CIRCULATORY DISORDERS

A class of N-substituted N-(α-triazolyltoluyl)pyrrole compounds described for use in treatment of circulatory disorders. Compounds of particular interest are angiotensin II antagonists of the formula STR1 wherein m is one; wherein R 1 is selected from methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, isobutyl, tert-butyl, 4-methylbutyl, n-pentyl, neopentyl, phenyl, benzyl, phenethyl, cyclohexyl, cyclohexylmethyl, cyclohexylethyl, cyclohexanoyl, 1-oxo-2-cyclohexylethyl, benzoyl, 1-oxo-2-phenethyl, 1-oxopropyl, 1-oxobutyl, 1-oxopentyl and 2-hydroxybutyl; wherein R 2 is selected from methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, isobutyl, tert-butyl, n-pentyl, isopentyl, neopentyl, phenyl, benzyl, phenethyl, cyclohexyl, cyclohexylmethyl, propylthio, butylthio, and hydroxyalkyl; wherein each of R 3, R 4, R 5, R 6, R 7, R 8, R 9 and R. sup.10 is independently selected from hydrido, halo, nitro, trifluoromethyl, hydroxy, alkoxy, cyano, carboxyl and methoxycarbonyl; with the proviso that at least one of R 5 and R 8 must be selected from COOH, SH, PO 3 H 2, SO 3 H, CONHNH 2, CONHNHSO 2 CF 3, OH, STR2 wherein each of R 42 and R 43 is independently selected from chloro, cyano, nitro, trifluoromethyl, methoxycarbonyl and trifluoromethylsulfonyl; or a tautomer thereof or a pharmaceutically-acceptable salt thereof. These compounds are particularly useful in treatment or control of hypertension and congestive heart failure.