144072-29-7

Basic information

• Product Name: BOC-4-AMINOBENZYLALCOHOL
• Synonyms: TERT-BUTYL 4-(HYDROXYMETHYL)PHENYLCARBAMATE;BOC-4-AMINOBENZYLALCOHOL;CarbaMic acid N-[4-(hydroxyMethyl)phenyl]-1,1-diMethyl ester;4-(Boc-aMino)benzyl alcohol;tert-butyl N-[4-(hydroxyMethyl)phenyl]carbaMate;4-benzyl alcohol;tert-Butyl (4-(hydroxymethyl)
• CAS NO: 144072-29-7
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.27
• Product Categories: CMLLYL
• Mol File: 144072-29-7.mol
• Article Data: 34

Chemical Properties

• Melting Point: 74-76 °C
• Boiling Point: 310.049 °C at 760 mmHg
• Flash Point: 141.313 °C
• Appearance: /
• Density: 1.161 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.565
• Storage Temp.: 2-8°C
• PKA: 13.66±0.70(Predicted)
• CAS DataBase Reference: BOC-4-AMINOBENZYLALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-4-AMINOBENZYLALCOHOL(144072-29-7)
• EPA Substance Registry System: BOC-4-AMINOBENZYLALCOHOL(144072-29-7)

Safety Data

• Hazardous Substances Data: 144072-29-7(Hazardous Substances Data)

Usage

General Description

BOC-4-aminobenzyl alcohol, also known as tert-butoxycarbonyl-4-aminobenzyl alcohol, is a chemical compound that is used as a building block in organic synthesis. It contains a benzene ring with an amino group and a hydroxyl group attached to it, as well as a tert-butoxycarbonyl (BOC) protecting group. BOC-4-AMINOBENZYLALCOHOL is commonly used in the pharmaceutical industry for the synthesis of various drugs and biologically active molecules. It is a versatile reagent that can be used in the preparation of a wide range of organic compounds, making it valuable in the field of medicinal chemistry and drug discovery.

InChI:InChI=1/C12H17NO3/c1-12(2,3)16-11(15)13-10-6-4-9(8-14)5-7-10/h4-7,14H,8H2,1-3H3,(H,13,15)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 623-04-1 4-aminobenzenemethanol 
• 94-09-7 p-aminoethylbenzoate 
• 150-13-0 4-amino-benzoic acid 
• 34619-03-9 tert-butyldicarbonate 
• 1239374-04-9 tert-butyl 4-(hydroxymethyl)phenyl(3-perfluorooctylpropoxy)carbamate 
• 66493-39-8 4-(N-tert-butoxycarbonyl)aminobenzoic acid 
• 144072-30-0 4-((tert-butoxycarbonyl)amino)benzaldehyde 
• 110969-44-3 4-tert-butyloxycarbonylaminobenzoic acid ethyl ester 

Downstream Products

• 144072-30-0 4-((tert-butoxycarbonyl)amino)benzaldehyde 
• 239074-27-2 4-(1,1-dimethylethoxycarbonylamino)benzylbromide 
• 252919-04-3 4-((tert-butoxycarbonyl)amino)benzyl methanesulfonate 
• 612530-89-9 {4-[5-(2,4-dimethoxybenzyl)-1,1,4-trioxo-1,2,5-thiadiazolidin-2-ylmethyl]phenyl}-carbamic acid t-butyl ester 
• 887245-04-7 2,2-bis-(4'-[3''-chloropropanamido]phenyl)-5,5-bi-1H-benzimidazole 
• 887245-02-5 2,2-bis(4'-[N-(tert-butoxycarbonyl)amino]phenyl)-5,5-bi-1H-benzimidazole 
• 4402-17-9 4,4'-(1H,1'H-[5,5'-bibenzo[d]imidazole]-2,2'-diyl)dianiline 
• 785827-88-5 diphenyl α-N-(benzyloxycarbonyl)amino(4-aminophenyl)methanephosphonate 
• 934622-37-4 benzyl 2-(4-aminophenyl)-1-(diphenoxyphosphoryl)ethylcarbamate 
• 695171-95-0 diphenyl 1-benzyloxycarbonylamino-2-(4-(tert-butyloxycarbonylamino)phenyl)ethanephosphonate 
• 785827-90-9 C₃₀H₃₇N₄O₇P 
• 913239-29-9 diphenyl 1-amino-2-(4-(N,N'-bis(tert-butyloxycarbonyl)guanidino)phenyl)ethyl-phosphonate 
• 695172-01-1 diphenyl benzyloxycarbonylamino-(4-(N,N'-bis(tert-butyloxycarbonyl)guanyl)phenyl)methanephosphonate 
• 695172-02-2 diphenyl 1-benzyloxycarbonylamino-2-(4-(N,N'-bis(tert-butyloxycarbonyl)guanyl)phenyl)ethanephosphonate 

Relevant articles and documents

Synthesis of rigid photoswitchable hemithioindigo ω-amino acids

The synthesis of novel N-Boc- and N-Fmoc protected hemithioindigo-based ω-amino acids is described. An approach to modulate the thermal stability of a hemithioindigo subunit is presented. Placing the amino-group in the stilbene part from the para- to meta

Methanesulfinylation of Benzyl Halides with Dimethyl Sulfoxide

A phenyltrimethylammonium tribromide-mediated nucleophilic substitution/oxygen transformation reaction of benzyl halides with DMSO has been developed. In this transition-metal-free reaction, DMSO acts as not only a solvent but also a "S(O)Me" source, thus providing a convenient method for the efficient and direct synthesis of various benzyl methyl sulfoxides.

CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS

The invention relates to inhibitors of PI5P4K inhibitors useful in the treatment of cancers, neurodegenerative diseases, inflammatory disorders, and metabolic diseases, having the Formula (I); where A1, A2, G, R1, R2, R3, R4, and W are described herein.