1440756-16-0Relevant articles and documents
Rh[III]-catalyzed C-H amidation using aroyloxycarbamates to give N-Boc protected arylamines
Grohmann, Christoph,Wang, Honggen,Glorius, Frank
supporting information, p. 3014 - 3017 (2013/07/26)
The Rh(III)-catalyzed amidation of C(sp2)-H bonds by the use of electron-deficient aroyloxycarbamates as efficient electrophilic amidation partners is reported. The reaction proceeded under mild conditions with broad functional group tolerance, and pyridine and O-methyl hydroxamic acids serve as efficient directing groups, giving access to valuable N-Boc protected arylamines (also Fmoc and Cbz). Preliminary mechanistic experiments are discussed.