144128-42-7 Usage
Description
(1E)-7-Chloro-3-(3,4-dichlorophenyl)-1-[(1-ethyl-3-piperidinyl)imino]10-hydroxy-1,3,4,10-tetrahydro-9(2H)-acridinone is a complex organic compound belonging to the acridine class. It features a 10-hydroxy-1,3,4,10-tetrahydro-9(2H)-acridinone core with a 7-chloro-3-(3,4-dichlorophenyl) and a 1-ethyl-3-piperidinyl functional group attached. Acridines are known for their potential applications in various biological and medical fields, including antimicrobial, antiviral, and antitumor properties, as well as their use as DNA-binding agents and fluorescent dyes.
Uses
Used in Pharmaceutical Industry:
(1E)-7-Chloro-3-(3,4-dichlorophenyl)-1-[(1-ethyl-3-piperidinyl)imino]10-hydroxy-1,3,4,10-tetrahydro-9(2H)-acridinone is used as a potential pharmaceutical agent for its antimicrobial, antiviral, and antitumor properties. Its unique structure allows it to interact with biological targets, making it a candidate for further research and development in the treatment of various diseases and conditions.
Used in Research Applications:
In the field of scientific research, (1E)-7-Chloro-3-(3,4-dichlorophenyl)-1-[(1-ethyl-3-piperidinyl)imino]10-hydroxy-1,3,4,10-tetrahydro-9(2H)-acridinone serves as a subject of study for understanding its biological and chemical properties. Its potential as a DNA-binding agent and fluorescent dye makes it valuable for research in molecular biology, genetics, and cell biology.
Further research is necessary to fully explore the capabilities and applications of (1E)-7-Chloro-3-(3,4-dichlorophenyl)-1-[(1-ethyl-3-piperidinyl)imino]10-hydroxy-1,3,4,10-tetrahydro-9(2H)-acridinone, as its complex structure and potential uses in various industries warrant a deeper understanding of its properties and interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 144128-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,1,2 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 144128-42:
(8*1)+(7*4)+(6*4)+(5*1)+(4*2)+(3*8)+(2*4)+(1*2)=107
107 % 10 = 7
So 144128-42-7 is a valid CAS Registry Number.
144128-42-7Relevant articles and documents
Synthesis and Antimalarial Properties of 1-Imino Derivatives of 7-Chloro-3-substituted-3,4-dihydro-1,9(2H,10H)-acridinediones and Related Structures
Kesten, Stephen J.,Degnan, Margaret J.,Hung, Jocelyn,McNamara, Dennis J.,Ortwine, Daniel F.,et al.
, p. 3429 - 3447 (2007/10/02)
To improve upon the activity and properties of the 3-aryl-7-chloro-3,4-dihydro-1,9(2H,10H)-acridinediones, a variety of 1-imino derivatives (3) were prepared and shown to be highly active antimalarial agents in both rodents and primates.Among structural modifications prepared, including N10-alkyl and C2-substituted analogs, removal of the C9 oxygen, and introduction of an imino side chain at C9, the imines of the N10-H acridinediones were the most active compounds obtained.The imino derivative of7-chloro-3-(2,4-dichlorophenyl)-3,4-dihydro-1,9(2H,10H)-acridinedione (9aa) proved to be highly active in advanced studies in primates.