144256-11-1

Basic information

• Product Name: (4S)-(2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4- hydroxybenzene) propanoic acid,methyl ester (Landiolol)
• Synonyms: (4S)-(2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4- hydroxybenzene) propanoic acid,methyl ester (Landiolol);((S)-2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 3-(4-hydroxyphenyl)propanoate;Benzenepropanoic acid, 4-hydroxy-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl ester;4-Hydroxybenzenepropanoic acid [(4S)-2,2-diMethyl-1,3-dioxolan-4-yl]Methyl ester;4S)-(2,2-diMethyl-1,3-dioxolan-4-yl)-3-(4-hydroxybenzene) propanoicacid,Methyl ester;Landiolol HCl PI-1;4-Hydroxybenzenepropanoic acid [(4S)-2,2-dimethyl-1,3
• CAS NO: 144256-11-1
• Molecular Formula: C₁₅H₂₀O₅
• Molecular Weight: 280.32
• EINECS: 1806241-263-5
• Product Categories: APIs Intermediate
• Mol File: 144256-11-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 409.21 °C at 760 mmHg
• Flash Point: 147.875 °C
• Appearance: /
• Density: 1.156
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.515
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (4S)-(2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4- hydroxybenzene) propanoic acid,methyl ester (Landiolol)(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-(2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4- hydroxybenzene) propanoic acid,methyl ester (Landiolol)(144256-11-1)
• EPA Substance Registry System: (4S)-(2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4- hydroxybenzene) propanoic acid,methyl ester (Landiolol)(144256-11-1)

Safety Data

• Hazardous Substances Data: 144256-11-1(Hazardous Substances Data)

Usage

Description

(4S)-(2,2-dimethyl-1,3-dioxolan-4-yl)-3-(4-hydroxybenzene)propanoic acid,methyl ester (Landiolol) is a white crystalline powder that serves as a useful research chemical compound with potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
Landiolol is used as an active pharmaceutical ingredient for the development of medications targeting specific health conditions. Its chemical properties make it a promising candidate for drug discovery and formulation.
Used in Chemical Research:
As a research chemical compound, Landiolol is utilized in the field of chemical research to study its properties, interactions, and potential applications in creating new compounds or improving existing ones.
Used in Material Science:
Landiolol's unique chemical structure may have potential applications in material science, where it could be used to develop new materials with specific properties or to enhance the performance of existing materials.

InChI:InChI=1/C15H20O5/c1-15(2)19-10-13(20-15)9-18-14(17)8-5-11-3-6-12(16)7-4-11/h3-4,6-7,13,16H,5,8-10H2,1-2H3/t13-/m1/s1

Upstream product

• 501-97-3 4-hydroxyphenylpropionic acid 
• 23735-43-5 (S)-1-O-tosyl-2,3-O-isopropylideneglycerol 
• 23788-74-1 (R)-2,2-dimethyl-1,3-dioxolane-4-ylmethyl p-toluenesulfonate 

Downstream Products

• 144256-12-2 2,2-dimethyl-1,3-dioxolan-4S-ylmethyl 3-<4-<2(S),3-epoxypropoxy>phenyl>propionate 
• 133242-64-5 3-[4-((S)-1-Oxiranylmethoxy)-phenyl]-propionic acid (R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 133242-30-5 2,2-dimethyl-1,3-dioxolan-4S-ylmethyl 3-<4-<3-<2-(morpholinocarbonylamino)ethylamino>-2S-hydroxypropoxy>phenyl>propionate 
• 133242-29-2 3-[4-((S)-2-Hydroxy-3-{2-[(morpholine-4-carbonyl)-amino]-ethylamino}-propoxy)-phenyl]-propionic acid (R)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 144481-98-1 Landiolol hydrochloride 
• 1253907-79-7 landiolol hydrochloride 

Relevant articles and documents

Preparation method of landiolol hydrochloride

The invention provides a preparation method of landiolol hydrochloride. The preparation method utilizes cheap and easily available raw materials. A key reaction utilizes a phase transfer catalysis method so reaction time is shortened. The preparation meth