1443119-76-3

Basic information

• Product Name: [(5-bromo-2-fluorobenzyl)oxy](tertbutyl)diphenylsilane
• Synonyms: [(5-bromo-2-fluorobenzyl)oxy](tertbutyl)diphenylsilane
• CAS NO: 1443119-76-3
• Molecular Weight: 443.431
• Mol File: 1443119-76-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(5-bromo-2-fluorobenzyl)oxy](tertbutyl)diphenylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: [(5-bromo-2-fluorobenzyl)oxy](tertbutyl)diphenylsilane(1443119-76-3)
• EPA Substance Registry System: [(5-bromo-2-fluorobenzyl)oxy](tertbutyl)diphenylsilane(1443119-76-3)

Safety Data

• Hazardous Substances Data: 1443119-76-3(Hazardous Substances Data)

Upstream product

• 93777-26-5 5-bromo-2-fluorobenzaldehyde 
• 99725-13-0 (5-bromo-2-fluorophenyl)methanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1443119-77-4 (1S)-1,5-anhydro-2,3,4,6-tetra-O-benzyl-1-[4-fluoro-3-(hydroxymethyl)phenyl]-D-glucitol 
• 1443119-79-6 (1S)-1,5-anhydro-2,3,4,6-tetra-O-benzyl-1-[3-(bromomethyl)-4-fluorophenyl]-D-glucitol 
• 1443119-81-0 (1S)-2,3,4,6-tetra-O-benzyl-1,5-anhydro-1-[3-(azulen-2-ylmethyl)-4-fluorophenyl]-D-glucitol 
• 1443119-80-9 (1S)-1,5-anhydro-1-[3-(azulen-2-ylmethyl)-4-fluorophenyl]-D-glucitol 

Relevant articles and documents

Synthesis and biological evaluation of C-glucosides with azulene rings as selective SGLT2 inhibitors for the treatment of type 2 diabetes mellitus: Discovery of YM543

Here, a series of C-glucosides with azulene rings in the aglycon moiety was synthesized and the inhibitory activities toward hSGLT1 and hSGLT2 were evaluated. Starting from the azulene derivative 7 which had relatively good SGLT2 inhibitory activity, comp