1443224-88-1

Basic information

• Product Name: C₁₄H₁₄N₂O₃
• Synonyms: C₁₄H₁₄N₂O₃
• CAS NO: 1443224-88-1
• Molecular Weight: 258.277
• Mol File: 1443224-88-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₄H₁₄N₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₄H₁₄N₂O₃(1443224-88-1)
• EPA Substance Registry System: C₁₄H₁₄N₂O₃(1443224-88-1)

Safety Data

• Hazardous Substances Data: 1443224-88-1(Hazardous Substances Data)

Upstream product

• 6190-46-1 methyl (2E,4E)-5-(benzo[d][1,3]dioxol-5-yl)penta-2,4-dienoate 

Relevant articles and documents

Natural-product-based insecticidal agents 14. Semisynthesis and insecticidal activity of new piperine-based hydrazone derivatives against Mythimna separata Walker in vivo

In continuation of our program aimed at the discovery and development of natural-product-based insecticidal agents, twenty-six new piperine-based hydrazone derivatives were synthesized from piperine, an alkaloid isolated from Piper nigrum Linn. The single-crystal structures of 6c, 6q and 6w were unambiguously confirmed by X-ray crystallography. Their insecticidal activity was evaluated against the pre-third-instar larvae of Mythimna separata Walker in vivo. Especially compounds 6b, 6i and 6r, the final mortality rates of which, at the concentration of 1 mg/mL, were 62.1%, 65.5% and 65.5%, respectively, exhibited more pronounced insecticidal activity compared to toosendanin at 1 mg/mL, a commercial botanical insecticide isolated from Melia azedarach. It suggested that introduction of the substituents at the C-2 position on the phenyl ring of the hydrazone derivatives was important for their insecticidal activity.